Radiological features of mixed connective tissue disease and scleroderma--systemic lupus erythematosus overlap.

The radiological, clinical, and laboratory features found in seven patients with scleroderma-SLE overlap, including three with mixed connective tissue disease (MCTD), are described. There were no distinctive roentgenographic features which differentiated those with MCTD from the others with a clinical overlap syndrome of scleroderma and SLE. When features of both coexist in a single patient the radiologist may be the first to suggest the correct diagnosis of overlap syndrome of MCTD.