Pines A, Kaplinsky N, Goldhammer E, Bregman J, Frankl O
Postgrad Med J. 1982 May;58(679):297-8. doi: 10.1136/pgmj.58.679.297.
Oesophageal involvement is known to be one of the most severe and resistant manifestations of connective tissue diseases, mainly progressive systemic sclerosis (PSS). A patient who had manifestations of systemic lupus erythematosus, PSS and polymyositis is described. Since some features of mixed connective tissue disease (MCTD) respond to corticosteroid treatment, fluocortolone was administered and both clinical and radiological remission of the oesophageal involvement were observed. At the same time, there was also a marked improvement of the cutaneous lesions. In view of the described observation, it seems advisable to try this treatment for oesophageal manifestations of MCTD.
食管受累是已知结缔组织病最严重且难治的表现之一，主要见于进行性系统性硬化症（PSS）。本文描述了一名患有系统性红斑狼疮、PSS和多发性肌炎表现的患者。由于混合性结缔组织病（MCTD）的一些特征对皮质类固醇治疗有反应，因此给予氟可的龙治疗，观察到食管受累的临床和放射学表现均得到缓解。同时，皮肤病变也有明显改善。鉴于上述观察结果，对于MCTD的食管表现尝试这种治疗似乎是可取的。
