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空气污染与医生上门出诊:1991 - 1995年法国大巴黎地区空气污染对公众健康影响监测ERPURS系统的结果。城市污染对健康的风险评估。

Air pollution and doctors' house calls: results from the ERPURS system for monitoring the effects of air pollution on public health in Greater Paris, France, 1991-1995. Evaluation des Risques de la Pollution Urbaine pour la Santé.

作者信息

Medina S, Le Tertre A, Quénel P, Le Moullec Y, Lameloise P, Guzzo J C, Festy B, Ferry R, Dab W

机构信息

Regional Observatory of Health (ORS), Paris, France.

出版信息

Environ Res. 1997 Oct;75(1):73-84. doi: 10.1006/enrs.1997.3773.

Abstract

This study examines short-term relationships between doctors' house calls and urban air pollution in Greater Paris for the period 1991-1995. Poisson regressions using nonparametric smoothing functions controlled for time trend, seasonal patterns, pollen counts, influenza epidemics, and weather. The relationship between asthma visits and air pollution was stronger for children. A relative risk (RRP95/P5) of 1.32 [95% confidence interval (CI) = 1.17-1.47)] was observed for an increase from the 5th to the 95th percentile (7-51 micrograms/m3) in daily concentrations of black smoke (BS). The risks for 24-hr sulfur dioxide and nitrogen dioxide levels were in the same range. Cardiovascular conditions, considered globally, showed weaker associations than angina pectoris/myocardial infarction, for which RRP95/P5 was 1.63 (95% CI = 1.10-2.41) in relation to ozone ambient levels. Eye conditions were exclusively related to ozone (RRP95/P5 = 1.17, 95% CI 1.02-1.33). Asthma visits and ozone showed an interaction with minimum temperature: an effect was observed only at 10 degrees C or higher. In two-pollutant models including BS with, successively, SO2, NO2, and O3, only BS and O3 effects remained stable. Along with mortality and hospital admissions, house call activity data, available on a regular basis, may be a sensitive indicator for monitoring health effects related to air pollution.

摘要

本研究调查了1991 - 1995年大巴黎地区医生上门问诊与城市空气污染之间的短期关系。使用非参数平滑函数的泊松回归对时间趋势、季节模式、花粉计数、流感流行情况和天气进行了控制。儿童哮喘就诊与空气污染之间的关系更为密切。黑烟(BS)日浓度从第5百分位数增加到第95百分位数(7 - 51微克/立方米)时,观察到相对风险(RRP95/P5)为1.32 [95%置信区间(CI)= 1.17 - 1.47]。24小时二氧化硫和二氧化氮水平的风险处于同一范围。总体而言,心血管疾病的关联比心绞痛/心肌梗死弱,对于心绞痛/心肌梗死,相对于臭氧环境水平,RRP95/P5为1.63(95% CI = 1.10 - 2.41)。眼部疾病仅与臭氧有关(RRP95/P5 = 1.17,95% CI 1.02 - 1.33)。哮喘就诊与臭氧与最低温度存在交互作用:仅在10摄氏度或更高温度下观察到影响。在依次包含BS与SO2、NO2和O3的双污染物模型中,只有BS和O3的影响保持稳定。与死亡率和住院人数一样,定期可得的上门问诊活动数据可能是监测与空气污染相关健康影响的敏感指标。

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