Petridou E, Trichopoulos D, Kravaritis A, Pourtsidis A, Dessypris N, Skalkidis Y, Kogevinas M, Kalmanti M, Koliouskas D, Kosmidis H, Panagiotou J P, Piperopoulou F, Tzortzatou F, Kalapothaki V
Department of Hygiene and Epidemiology, Athens University Medical School, Greece.
Int J Cancer. 1997 Nov 4;73(3):345-8. doi: 10.1002/(sici)1097-0215(19971104)73:3<345::aid-ijc7>3.0.co;2-#.
Residential proximity to electrical power lines of different voltage in relation to childhood leukemia was investigated through a case-control study undertaken in Greece during 1993-1994. The study comprised 117 incident cases of childhood leukemia and 202 age-, gender- and place-of-residence-matched controls. Four measures of exposure to magnetic fields were developed, using data provided by the Public Power Corporation of Greece: Voltage (V) divided by the distance (d), V/d2, V/d3 and an adaptation of the Wertheimer-Leeper code. Conditional-logistic-regression modeling was used to adjust for potential confounding influences of 18 variables. No significant trends of childhood leukemia risk with increasing exposure levels were noted, nor were there statistically significant elevations of disease risk at the higher exposure levels in each measure of exposure. These results do not support a causal link between residential proximity to electrical high-voltage wires and childhood leukemia risk, but in themselves do not refute a weak empirical association.
通过1993 - 1994年在希腊进行的一项病例对照研究,调查了儿童白血病与居住在不同电压等级电线附近之间的关系。该研究包括117例儿童白血病新发病例和202名年龄、性别和居住地点匹配的对照。利用希腊国家电力公司提供的数据,制定了四种磁场暴露测量方法:电压(V)除以距离(d)、V/d²、V/d³以及对韦特海默 - 利珀代码的一种改编。采用条件逻辑回归模型来调整18个变量的潜在混杂影响。未发现随着暴露水平增加儿童白血病风险有显著趋势,在每种暴露测量的较高暴露水平下,疾病风险也没有统计学上的显著升高。这些结果不支持居住在高压电线附近与儿童白血病风险之间存在因果联系,但就其本身而言也不排除存在微弱的经验关联。