异常磷脂半溶血双磷脂酸在高尔基体复合物中的异质性分布。
Heterogeneous distribution of the unusual phospholipid semilysobisphosphatidic acid through the Golgi complex.
作者信息
Cluett E B, Kuismanen E, Machamer C E
机构信息
Department of Cell Biology and Anatomy, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2105, USA.
出版信息
Mol Biol Cell. 1997 Nov;8(11):2233-40. doi: 10.1091/mbc.8.11.2233.
Abstract
To investigate the distribution of lipids through the Golgi complex, we analyzed the envelopes of several viruses that assemble in different subcompartments of the Golgi, as well as subcellular fractions. Our results indicate that each Golgi subcompartment has a distinct phospholipid composition due mainly to differences in the relative amounts of semilysobisphosphatidic acid (SLBPA), sphingomyelin, phosphatidylserine, and phosphatidylinositol. Interestingly, SLBPA is enriched in the adjacent Golgi networks compared with the Golgi stack, and this enrichment varies with cell type. The heterogeneous distribution of SLBPA through the Golgi complex suggests it may play an important role in the structure and/or function of this organelle.
摘要
为了研究脂质在高尔基体中的分布，我们分析了几种在高尔基体不同亚区组装的病毒包膜以及亚细胞组分。我们的结果表明，每个高尔基体亚区都有独特的磷脂组成，这主要是由于半溶血双磷脂酸（SLBPA）、鞘磷脂、磷脂酰丝氨酸和磷脂酰肌醇相对含量的差异。有趣的是，与高尔基体堆叠相比，SLBPA在相邻的高尔基体网络中更为富集，且这种富集因细胞类型而异。SLBPA在高尔基体中的异质分布表明它可能在该细胞器的结构和/或功能中发挥重要作用。
相似文献
1
Heterogeneous distribution of the unusual phospholipid semilysobisphosphatidic acid through the Golgi complex.异常磷脂半溶血双磷脂酸在高尔基体复合物中的异质性分布。
Mol Biol Cell. 1997 Nov;8(11):2233-40. doi: 10.1091/mbc.8.11.2233.
2
The envelope of vaccinia virus reveals an unusual phospholipid in Golgi complex membranes.
J Cell Sci. 1996 Aug;109 ( Pt 8):2121-31. doi: 10.1242/jcs.109.8.2121.
3
Subcellular localization of three degeneration-associated phospholipids in cultured hamster fibroblasts (BHK21 cells).
Biochim Biophys Acta. 1979 Sep 28;574(3):461-70. doi: 10.1016/0005-2760(79)90242-x.
4
Organelle-specific antibodies: production of antibodies to Golgi subcompartments.细胞器特异性抗体：针对高尔基体亚区室的抗体产生
Prog Clin Biol Res. 1988;270:129-39.
5
Sphingomyelin-enriched microdomains at the Golgi complex.高尔基体复合体中富含鞘磷脂的微结构域。
Mol Biol Cell. 2001 Jun;12(6):1819-33. doi: 10.1091/mbc.12.6.1819.
6
Targeting of viral glycoproteins to the Golgi complex.病毒糖蛋白靶向高尔基体复合体。
Trends Microbiol. 1993 Jul;1(4):124-30. doi: 10.1016/0966-842x(93)90126-c.
7
The distribution of 215-kilodalton mannose 6-phosphate receptors within cis (heavy) and trans (light) Golgi subfractions varies in different cell types.215千道尔顿甘露糖6-磷酸受体在顺式（重）和反式（轻）高尔基体亚组分中的分布在不同细胞类型中有所不同。
Proc Natl Acad Sci U S A. 1987 Dec;84(24):9001-5. doi: 10.1073/pnas.84.24.9001.
8
The phospholipid composition of extracellular herpes simplex virions differs from that of host cell nuclei.细胞外单纯疱疹病毒粒子的磷脂组成与宿主细胞核的磷脂组成不同。
Virology. 1994 May 1;200(2):831-6. doi: 10.1006/viro.1994.1252.
9
Dissection of the Golgi complex. II. Density separation of specific Golgi functions in virally infected cells treated with monensin.高尔基体复合体的剖析。II. 用莫能菌素处理的病毒感染细胞中特定高尔基体功能的密度分离
J Cell Biol. 1983 Mar;96(3):851-6. doi: 10.1083/jcb.96.3.851.
10
Polymorphism and structural maturation of bunyamwera virus in Golgi and post-Golgi compartments.布尼亚姆韦拉病毒在高尔基体和高尔基体后区室中的多态性与结构成熟
J Virol. 2003 Jan;77(2):1368-81. doi: 10.1128/jvi.77.2.1368-1381.2003.
引用本文的文献
1
A malaria parasite phospholipase facilitates efficient asexual blood stage egress.疟原虫磷脂酶促进有性血期的高效外溢。
PLoS Pathog. 2023 Jun 23;19(6):e1011449. doi: 10.1371/journal.ppat.1011449. eCollection 2023 Jun.
2
Assembly and Cellular Exit of Coronaviruses: Hijacking an Unconventional Secretory Pathway from the Pre-Golgi Intermediate Compartment via the Golgi Ribbon to the Extracellular Space.冠状病毒的组装和细胞外排出：通过高尔基带从前高尔基中间隔劫持非常规分泌途径到细胞外空间。
Cells. 2021 Feb 26;10(3):503. doi: 10.3390/cells10030503.
3
Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum.双嘧达莫通过将 SCAP-SREBP 保留在内质网中抑制脂肪生成基因表达。
Cell Chem Biol. 2021 Feb 18;28(2):169-179.e7. doi: 10.1016/j.chembiol.2020.10.003. Epub 2020 Oct 22.
4
Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif.PH 结构域与神经酰胺转移蛋白（CERT）中磷酸肌醇的结合受相邻丝氨酸重复基序的高磷酸化抑制。
J Biol Chem. 2018 Jul 13;293(28):11206-11217. doi: 10.1074/jbc.RA118.002465. Epub 2018 May 30.
5
Coronavirus S protein-induced fusion is blocked prior to hemifusion by Abl kinase inhibitors.Abl 激酶抑制剂在半融合前阻止冠状病毒 S 蛋白诱导的融合。
J Gen Virol. 2018 May;99(5):619-630. doi: 10.1099/jgv.0.001047. Epub 2018 Mar 20.
6
Mast cells and influenza a virus: association with allergic responses and beyond.肥大细胞与甲型流感病毒：与过敏反应及其他方面的关联
Front Immunol. 2015 May 18;6:238. doi: 10.3389/fimmu.2015.00238. eCollection 2015.
7
Alteration of the lipid profile in lymphomas induced by MYC overexpression.MYC 过表达诱导的淋巴瘤中脂质谱的改变。
Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10450-5. doi: 10.1073/pnas.1409778111. Epub 2014 Jul 3.
8
Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT).神经酰胺转运蛋白（CERT）的pleckstrin 同源结构域与高尔基体结合的结构基础。
J Biol Chem. 2012 Sep 28;287(40):33706-18. doi: 10.1074/jbc.M112.367730. Epub 2012 Aug 6.
9
The kiss-and-run model of intra-Golgi transport.高尔基体内运输的亲吻-逃离模型。
Int J Mol Sci. 2012;13(6):6800-6819. doi: 10.3390/ijms13066800. Epub 2012 Jun 5.
10
Multiple phosphatidylinositol 3-kinases regulate vaccinia virus morphogenesis.多种磷酸肌醇 3-激酶调节痘苗病毒形态发生。
PLoS One. 2010 May 28;5(5):e10884. doi: 10.1371/journal.pone.0010884.
本文引用的文献
1
Traffic COPs and the formation of vesicle coats.运输COP蛋白与囊泡衣被的形成
Trends Cell Biol. 1996 Dec;6(12):468-73. doi: 10.1016/0962-8924(96)84943-9.
2
Functional rafts in cell membranes.细胞膜中的功能性筏区
Nature. 1997 Jun 5;387(6633):569-72. doi: 10.1038/42408.
3
Essential role for diacylglycerol in protein transport from the yeast Golgi complex.二酰基甘油在酵母高尔基体复合体蛋白质转运中的重要作用。
Nature. 1997 May 1;387(6628):101-5. doi: 10.1038/387101a0.
4
Golgi localization of glycosyltransferases: more questions than answers.糖基转移酶的高尔基体定位：问题多于答案。
Glycobiology. 1997 Feb;7(1):1-13. doi: 10.1093/glycob/7.1.1-b.
5
Immunocytochemical analysis of Uukuniemi virus budding compartments: role of the intermediate compartment and the Golgi stack in virus maturation.乌昆耶米病毒出芽区室的免疫细胞化学分析：中间区室和高尔基体堆叠在病毒成熟中的作用
J Virol. 1997 Feb;71(2):1162-72. doi: 10.1128/JVI.71.2.1162-1172.1997.
6
The envelope of vaccinia virus reveals an unusual phospholipid in Golgi complex membranes.
J Cell Sci. 1996 Aug;109 ( Pt 8):2121-31. doi: 10.1242/jcs.109.8.2121.
7
Tetraoleoylpyrophosphatidic acid: a four acyl-chain lipid which forms a hexagonal II phase with high curvature.四油酰焦磷酸：一种具有四条酰基链的脂质，可形成具有高曲率的六方II相。
Biophys J. 1996 Mar;70(3):1402-6. doi: 10.1016/S0006-3495(96)79698-4.
8
Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.磷脂酶D介导ADP核糖基化因子依赖性高尔基体被膜小泡形成的证据。
J Cell Biol. 1996 Jul;134(2):295-306. doi: 10.1083/jcb.134.2.295.
9
COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast.在酵母中，COP I和COP II包被囊泡直接从内质网出芽形成。
Cell. 1995 Dec 29;83(7):1183-96. doi: 10.1016/0092-8674(95)90144-2.
10
Assembly of vaccinia virus: role of the intermediate compartment between the endoplasmic reticulum and the Golgi stacks.痘苗病毒的组装：内质网与高尔基体堆栈之间中间区室的作用。
J Cell Biol. 1993 May;121(3):521-41. doi: 10.1083/jcb.121.3.521.
Zotero 插件