Petridou E, Polychronopoulou A, Kouri N, Karpathios T, Koussouri M, Messaritakis Y, Mathioudakis Y, Siafas K, Tsitsika H, Zografos E
Department of Hygiene and Epidemiology, Athens University Medical School, Greece.
J Toxicol Clin Toxicol. 1997;35(6):669-75. doi: 10.3109/15563659709001253.
To estimate the incidence of unintentional childhood injuries resulting from accidental poisonings in the Greater Athens area and to ascertain what fraction of this incidence could be linked to specified conditions, amenable to preventive interventions.
Prospective study over 12 months of 670 children hospitalized 224 hours for accidental poisoning. Site: Two pediatric hospitals and three smaller units in Greater Athens admitting children < or = 15 years old. Information was recorded in a semistructured questionnaire and the data were analyzed through simple stratification by one or more variables. Results Accidental poisoning requiring hospitalization > or = 24 hours was 50% higher among boys than among girls, peaked towards the end of the second year, and declined sharply after the fourth year of life with an estimated incidence of 500 cases per 100,000 among children > or = 5 years old. Cigarettes were the most common agent among infants, whereas medicinal products dominated all other childhood periods. Detergents, petroleum products, and pesticides each contributed about 10% of all poisonings with detergents peaking during the second year of life, petroleum products during the third year, and pesticides remaining constant, in proportional terms, throughout childhood. During the working hours of the day the incidence of poisonings was 80% higher than during the late afternoon and evening hours or the weekends, the times when both parents are usually at home; the excess was statistically significant. The presence of both parents at home in the afternoon hours was associated with an almost 50% reduction of hospitalized poisoning. The accessibility of products with poisoning potential was of major importance. Some specific conditions that led to the incident included storage of potentially poisoning products in the refrigerator, storage of such products in containers of innocuous products, without proper labeling, and parental errors in medication.
Unintentional childhood poisoning further reflects an interaction between inappropriate storage of consumer products and suboptimal supervision during the housekeeping hours of the day.
估算大雅典地区儿童意外中毒导致的意外伤害发生率,并确定该发生率中可归因于特定状况且适合采取预防干预措施的比例。
对因意外中毒住院224小时的670名儿童进行为期12个月的前瞻性研究。地点:大雅典地区的两家儿童医院和三个较小的收治15岁及以下儿童的科室。信息记录在半结构化问卷中,并通过按一个或多个变量进行简单分层对数据进行分析。结果:需要住院24小时及以上的意外中毒在男孩中的发生率比女孩高50%,在第二年年底达到峰值,在4岁以后急剧下降,估计5岁及以上儿童中的发生率为每10万人500例。香烟是婴儿中最常见的中毒源,而药品在儿童其他时期占主导地位。洗涤剂、石油产品和杀虫剂各占所有中毒事件的约10%,洗涤剂在第二年达到峰值,石油产品在第三年达到峰值,杀虫剂在整个儿童期按比例保持稳定。在白天的工作时间,中毒发生率比下午晚些时候、晚上或周末高80%,而在这些时段父母通常都在家;这种差异具有统计学意义。下午父母双方都在家与住院中毒发生率降低近50%相关。具有中毒潜在风险的产品的可获取性至关重要。导致中毒事件的一些具体状况包括将潜在中毒产品储存在冰箱中、将此类产品储存在无害产品容器中且未正确标注,以及父母用药错误。
儿童意外中毒进一步反映了消费品储存不当与白天家务时间监管不力之间的相互作用。