Department of Pediatrics, Archbishop Makarios Hospital, Nicosia, Cyprus,
Eur J Pediatr. 2010 Jul;169(7):833-8. doi: 10.1007/s00431-009-1124-8. Epub 2009 Dec 17.
Information on childhood poisonings in Cyprus is limited. Our objective was to examine the epidemiology of poisonings among children in Cyprus. All children up to 15 years of age admitted for poisoning to the Archbishop Makarios Hospital in Nicosia, Cyprus between 2005 and 2008 were included in our study. All hospital poisoning records were reviewed. A total of 257 children were admitted for poisoning. The mean age of children was 3.1 years, of which 83.7% were below the age of 5 years old, while 53% were boys. The poisoning hospitalizations accounted for about 3% of all admissions to the pediatric department during the study period (4 years). The annual cumulative incidence of childhood poisoning hospitalizations was 116 per 100,000 children. Medications accounted for 46.1% of all poisonings, the most frequent cause being paracetamol (9.8%), cardiovascular medications (5.3%), antitussive medications (4.5%), and other painkillers (4.1%). Another 37.6% of hospitalizations involved household products such as household cleaning products (11.8%), petroleum products (11.0%), and rodenticides (5.7%). Among children who ingested petroleum distillates, 55.6% developed clinical symptomatology. The vast majority of cases were accidental (93.8%). Suicidal cases involved children 8-14 years old, mainly girls, and the most frequent poisoning ingested was paracetamol (46.7%). Poisoning hospitalizations represent an important cause of morbidity among children in Cyprus. Preventive strategies should include the education of caregivers on the handling of medications and household products as well as legislation requiring child-resistant packaging for all medications and household products including petroleum distillates.
关于塞浦路斯儿童中毒的信息有限。我们的目的是研究塞浦路斯儿童中毒的流行病学。2005 年至 2008 年期间,我们将所有因中毒而入住塞浦路斯尼科西亚大主教马卡里奥斯医院的 15 岁以下儿童纳入研究。所有医院中毒记录均进行了审查。共有 257 名儿童因中毒住院。儿童的平均年龄为 3.1 岁,其中 83.7%年龄在 5 岁以下,53%为男孩。中毒住院占研究期间(4 年)儿科总住院人数的 3%左右。儿童中毒住院的年累积发病率为每 10 万儿童 116 例。药物占所有中毒的 46.1%,最常见的原因是对乙酰氨基酚(9.8%)、心血管药物(5.3%)、镇咳药(4.5%)和其他止痛药(4.1%)。另有 37.6%的住院涉及家用产品,如家用清洁产品(11.8%)、石油产品(11.0%)和灭鼠药(5.7%)。摄入石油馏分的儿童中,55.6%出现临床症状。绝大多数病例为意外(93.8%)。自杀病例涉及 8-14 岁儿童,主要为女孩,最常摄入的中毒药物为对乙酰氨基酚(46.7%)。中毒住院是塞浦路斯儿童发病的重要原因。预防策略应包括教育照顾者正确处理药物和家用产品,以及立法要求所有药物和家用产品(包括石油馏分)采用儿童防护包装。