Robinson L A, Howell D N, Wigfall D R, Foreman J W
Department of Pediatric Nephrology, Duke University Medical Center, Durham, NC 27710, USA.
Am J Kidney Dis. 1997 Nov;30(5):713-6. doi: 10.1016/s0272-6386(97)90498-4.
Renal disease is a frequent late complication of type I diabetes mellitus, occurring almost entirely in adult patients. Typical diabetic nephropathy is characterized by proteinuria, and by the histological lesions of mesangial expansion and basement membrane thickening. We report an interesting case of a 3-year-old boy who developed immune complex glomerulonephritis with nephrotic syndrome 2 months after the onset of insulin-dependent diabetes mellitus.
肾脏疾病是I型糖尿病常见的晚期并发症,几乎全部发生于成年患者。典型的糖尿病肾病以蛋白尿以及肾小球系膜扩张和基底膜增厚的组织学病变为特征。我们报告了一例有趣的病例,一名3岁男孩在胰岛素依赖型糖尿病发病2个月后出现了伴有肾病综合征的免疫复合物肾小球肾炎。