Goodrich R P, Sowemino-Coker S O, Weinstein R
Cryopharm Corporation, Pasadena, California, USA.
Curr Opin Hematol. 1994 Mar;1(2):162-9.
The desirability of extending the therapeutic benefits of erythrocyte transfusions beyond the currently available options is well established. Extended frozen storage of rare blood types, hemoglobin-based or artificial blood substitutes for treatment of short-term deficits in oxygen-carrying capacity, novel approaches to tissue oxygenation for cancer therapy, and efficient storage and availability of erythrocytes in military field installations are all potential applications of ongoing research and development efforts. This review explains the need for improvement in erythrocyte storage and development of blood substitutes, the current problems in the field, and the progress made toward solving these problems in the past year.
将红细胞输血的治疗益处扩展到现有选项之外的必要性已得到充分证实。稀有血型的延长冷冻保存、基于血红蛋白或人工血液替代品用于治疗短期携氧能力不足、用于癌症治疗的新型组织氧合方法以及军事野战设施中红细胞的高效储存和供应，都是正在进行的研发工作的潜在应用。本综述解释了改善红细胞储存和开发血液替代品的必要性、该领域当前存在的问题以及过去一年在解决这些问题方面取得的进展。
