老年人的克雅氏病
Creutzfeldt-Jakob disease in the elderly.
作者信息
de Silva R, Findlay C, Awad I, Harries-Jones R, Knight R, Will R
机构信息
National CJD Suveillance Unit, Western General Hospital, Edinburgh, UK.
出版信息
Postgrad Med J. 1997 Sep;73(863):557-9. doi: 10.1136/pgmj.73.863.557.
Abstract
Creutzfeldt-Jakob disease (CJD) is typically described as a pre-senile dementia. However, cases do occur in the elderly and a case of sporadic CJD in an 86-year-old patient is described. The database of the UK national surveillance unit has been studied, and the age-specific incidences for various age groups over the period 1980-93 calculated. Cases of CJD in those over 80 years old have been identified and their clinical characteristics examined. There is no evidence that CJD presents atypically in the elderly, or that large numbers of cases are being missed in the elderly due to poor ascertainment.
摘要
克雅氏病（CJD）通常被描述为早老性痴呆。然而，老年患者中确实会出现这种病例，本文描述了一例86岁散发性CJD患者。对英国国家监测单位的数据库进行了研究，并计算了1980 - 1993年期间各年龄组的年龄特异性发病率。已识别出80岁以上的CJD病例，并对其临床特征进行了检查。没有证据表明CJD在老年人中表现不典型，也没有证据表明由于确诊率低而导致大量老年病例被漏诊。
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