Lalonde R
Neurology Service, Hôtel-Dieu Hospital Research Center, Montréal, Quebec, Canada.
Int Rev Neurobiol. 1997;41:191-215. doi: 10.1016/s0074-7742(08)60352-9.
The importance of the hippocampus and its anatomical connections, including the medial septum, thalamic nuclei, and neocortical regions in many spatial tasks including the Morris water maze, has been emphasized. Studies in mutant mice with cerebellar atrophy and in rats with electrolytic lesions of the cerebellum have indicated that the cerebellum has a role in visuospatial and visuomotor processes in the Morris maze. Directional deficits in the water have also been noted in rats whose cerebellum was exposed to X-rays during different developmental stages. Cerebellar interactions with the superior colliculus, the hippocampus, and the neocortex via thalamic nuclei are suggested to be the basis of the cerebellar modulation of directional sense in maze tests.
海马体及其解剖学连接的重要性，包括内侧隔区、丘脑核团和新皮质区域在包括莫里斯水迷宫在内的许多空间任务中的重要性，已得到强调。对患有小脑萎缩的突变小鼠和小脑有电解损伤的大鼠的研究表明，小脑在莫里斯迷宫的视觉空间和视觉运动过程中发挥作用。在不同发育阶段小脑暴露于X射线的大鼠中，也观察到了水中的方向缺陷。小脑通过丘脑核团与上丘、海马体和新皮质的相互作用被认为是迷宫测试中方向感小脑调节的基础。
