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[心动过缓-心动过速综合征]

[The bradycardia-tachycardia syndrome].

作者信息

Salazar E, Cerda G, Pieniak M

出版信息

Arch Inst Cardiol Mex. 1976 Mar-Apr;46(2):134-47.

PMID:938155
Abstract

Disorders of the heart rhythm which consist basically of sinus bradicardia or sinus arrest correspond to a syndrome which has been named the sick sinus syndrome. Within the framework of this syndrome, there is a subgroup of alternating atrial bradycardia with episodes of atrial tachyarrhythmia. Generally known as the bradycardia-tachycardia syndrome, this subgroup is both electrophysiologically interesting and therapeutically challenging. This report is concerned with the experience obtained at the emergency ward and coronary care unit of the Instituto Nacional de Cardiología de México on the diagnosis and management of 8 patients with this syndrome. Various underlying heart conditions were present with predominance of ischemic heart disease. The clinical picture was dependent upon the hypoperfusion of vital organs secondary to the cardial arrhythmia. The most common symptoms were derived from cerebral circulatory deficit and coronary insufficiency. Half of the patients had moderate cardiac failure. All patients had spontaneous and transient loss of sinus function which lasted more than 2,000 msec. in seven. The bradycardia had a rate below 50 beats per minute in all cases except one. The tachyarrhythmias observed were atrial flutter, atrial fibrillation and paroxysmal supraventricular tachycardia. Three of the patients had more than one of these these tachyarrhythmias during the period of study. A discussion is made on the diagnosis of this syndrome by means of atrial pacing and interventions which modify either vagal or sympathetic tone. Considerations are also made on the frequent associated abnormality of the A-V functional tissues. Emphasis is placed on the problems encountered in the management of these patients. It is concluded that, in most cases, a satisfactory result may be obtained by the implantation of a permanent demand pacemaker associated to the administration of antiarrhythmic drugs.

摘要

基本由窦性心动过缓或窦性停搏组成的心律失常紊乱对应于一种已被命名为病态窦房结综合征的综合征。在该综合征的框架内,有一个交替性房性心动过缓伴房性快速心律失常发作的亚组。这个亚组通常被称为心动过缓 - 心动过速综合征,在电生理学上很有趣且在治疗上具有挑战性。本报告涉及墨西哥国家心脏病研究所急诊病房和冠心病监护病房对8例该综合征患者的诊断和管理经验。存在各种潜在的心脏疾病,以缺血性心脏病为主。临床表现取决于心律失常继发的重要器官灌注不足。最常见的症状源于脑循环不足和冠状动脉供血不足。一半的患者有中度心力衰竭。所有患者均有窦性功能的自发和短暂丧失,其中7例持续超过2000毫秒。除1例患者外,所有病例的心动过缓心率均低于每分钟50次。观察到的快速心律失常为心房扑动、心房颤动和阵发性室上性心动过速。在研究期间,3例患者有不止一种这些快速心律失常。文中讨论了通过心房起搏以及改变迷走神经或交感神经张力的干预措施来诊断该综合征。还考虑了房室功能组织常见的相关异常。重点强调了这些患者管理中遇到的问题。得出的结论是,在大多数情况下,通过植入永久性按需起搏器并联合使用抗心律失常药物可获得满意的结果。

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