Sudjic M M, Booth R
Biochem J. 1976 Feb 15;154(2):559-60. doi: 10.1042/bj1540559.
Rat brain contains 3-hydroxy-3-methylglutaryl-CoA reductase activity, but this enzyme is far more active in 7-day-old brain than in adult brain. This difference may partly explain why cholesterol biosynthesis is more rapid in growing than in adult rat brain.
大鼠大脑含有3-羟基-3-甲基戊二酰辅酶A还原酶活性,但这种酶在7日龄大脑中的活性远比在成年大脑中高。这种差异可能部分解释了为什么在生长中的大鼠大脑中胆固醇生物合成比成年大鼠大脑中更快。