CT肺密度测定法：CT数值直方图对样本体积的依赖性以及扫描协议可比性的影响
CT lung densitometry: dependence of CT number histograms on sample volume and consequences for scan protocol comparability.
作者信息
Kemerink G J, Kruize H H, Lamers R J, van Engelshoven J M
机构信息
Department of Radiology, University Hospital Mastricht, The Netherlands.
出版信息
J Comput Assist Tomogr. 1997 Nov-Dec;21(6):948-54. doi: 10.1097/00004728-199711000-00018.
PURPOSE
Our goals were to determine the dependence of CT number histograms of the lung on section thickness and reconstruction filter and to evaluate the consequences for scan protocol conformity required for universally comparable densitometry of the lungs.
METHOD
The effects of section thickness and reconstruction filter were parameterized with the CT's sample volume [V approximately (section thickness x in-plane resolution2)]. In a study of 31 patients, we determined as a function of V the following CT number histogram parameters: percentiles P(10) and P(90), pixel indexes PI(-905) and PI(-950), and standard deviation.
RESULTS
Patient histogram parameters depended strongly on sample volume. Large differences were found between protocols using 1 and 10 mm sections. For small variations in somewhat larger sample volumes (> 8 mm3), discrepancies were much smaller.
CONCLUSION
To obtain comparable histogram parameters, nearly identical sample volumes (> or = 8 mm3) should be used. When this condition is satisfied, available data suggest that universally comparable densitometry is feasible.
目的
我们的目标是确定肺部CT数值直方图对层厚和重建滤波器的依赖性，并评估肺部通用可比密度测定所需扫描方案一致性的影响。
方法
层厚和重建滤波器的影响通过CT的样本体积[V≈（层厚×平面内分辨率²）]进行参数化。在一项对31名患者的研究中，我们确定了作为V的函数的以下CT数值直方图参数：百分位数P(10)和P(90)、像素指数PI(-905)和PI(-950)以及标准差。
结果
患者直方图参数强烈依赖于样本体积。使用1毫米和10毫米层厚的方案之间存在很大差异。对于稍大样本体积（>8立方毫米）的小变化，差异要小得多。
结论
为了获得可比的直方图参数，应使用几乎相同的样本体积（≥8立方毫米）。当满足此条件时，现有数据表明通用可比密度测定是可行的。
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