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初乳和/或哺乳期母亲母乳中瘦素的存在:对新生儿食物摄入量调节的潜在作用。

Presence of leptin in colostrum and/or breast milk from lactating mothers: a potential role in the regulation of neonatal food intake.

作者信息

Casabiell X, Piñeiro V, Tomé M A, Peinó R, Diéguez C, Casanueva F F

机构信息

Complejo Universitario de Santiago, Department of Medicine, Spain.

出版信息

J Clin Endocrinol Metab. 1997 Dec;82(12):4270-3. doi: 10.1210/jcem.82.12.4590.

DOI:10.1210/jcem.82.12.4590
PMID:9398752
Abstract

In neonates both nutrients and regulatory factors are transferred from the mother to the suckling infant via milk. In the present work, it has been shown that human milk contains immunoreactive leptin which is identical to intact human leptin by criteria of charge, size, immunorecognition and SDS-PAGE mobility. In experimental animals it was demonstrated that leptin is transferred from the circulation to mothers' milk, then to the infant's stomach and afterwards to infant blood. Maternal leptin in milk may play a regulatory role in the suckling infant.

摘要

在新生儿中,营养物质和调节因子都通过乳汁从母亲传递给哺乳的婴儿。在目前的研究中,已经表明人乳中含有免疫反应性瘦素,根据电荷、大小、免疫识别和SDS-PAGE迁移率标准,它与完整的人瘦素相同。在实验动物中已证明,瘦素从循环系统转移到母乳中,然后进入婴儿的胃,之后进入婴儿血液。母乳中的母体瘦素可能对哺乳婴儿起到调节作用。

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