Malm C, Svensson M, Ekblom B, Sjödin B
Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden.
Acta Physiol Scand. 1997 Nov;161(3):379-84. doi: 10.1046/j.1365-201X.1997.00198.x.
This study investigated the effects of oral supplementation with ubiquinone-10 (Q10) (n = 9) compared with a placebo (n = 9) on aerobic and anaerobic physical performance over 22 days of supplementation. The supplementation period included 5 days of high intensity anaerobic training between days 11 and 14. The results demonstrated, that on an anaerobic (10 x 10 s) cycling test, the placebo group showed a significantly greater improvement than the Q10-group after a supplementation and training period (P < 0.001). Further, the Q10 group had a significantly lower increase in total work performed during the seven training sessions (15 x 10 s) compared with the placebo group (P < 0.001). There was a significant increase in maximal blood lactate accumulation during cycling in the both groups, when compared with levels before the training and recovery period. There was no significant difference between the groups, either in VO2max determined during running, or in submaximal and peak VO2, Rate of Perceived Exertion, respiratory quotient, blood lactate concentration or heart rate determined during submaximal and maximal cycling. Although insignificant (P = 0.1-0.3), there was evidence of higher submaximal VO2 (55-80% of VO2peak) during cycling in the Q10-group compared with the placebo group after training and recovery. It is concluded that with high intensity anaerobic training, there was a significantly greater increase in anaerobic performance in the placebo group compared with the Q10 group. The results suggest less increase in physical performance with Q10 supplement and high intensity anaerobic training, compared with placebo.
本研究调查了口服补充辅酶Q10（Q10）（n = 9）与安慰剂（n = 9）相比，在22天的补充期内对有氧和无氧身体机能的影响。补充期包括在第11天至14天之间进行5天的高强度无氧训练。结果表明，在无氧（10×10秒）自行车测试中，经过补充和训练期后，安慰剂组的改善明显大于Q10组（P < 0.001）。此外，与安慰剂组相比，Q10组在七次训练课程（15×10秒）中完成的总工作量增加明显更低（P < 0.001）。与训练和恢复期之前的水平相比，两组在骑自行车过程中的最大血乳酸积累均显著增加。在跑步过程中测定的最大摄氧量、在次最大和峰值摄氧量、主观用力程度、呼吸商、血乳酸浓度或在次最大和最大自行车运动过程中测定的心率方面，两组之间均无显著差异。尽管不显著（P = 0.1 - 0.3），但有证据表明，在训练和恢复后，Q10组在骑自行车过程中的次最大摄氧量（VO2峰值的55 - 80%）高于安慰剂组。结论是，在高强度无氧训练中，与Q10组相比，安慰剂组的无氧性能显著提高。结果表明，与安慰剂相比，补充Q10和进行高强度无氧训练时身体机能的提高较少。
