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辅酶 Q 补充及其对人体运动表现的影响:恢复物质还是性能增强分子?

Coenzyme Q Supplementation and Its Impact on Exercise and Sport Performance in Humans: A Recovery or a Performance-Enhancing Molecule?

机构信息

Medical Services Shanghai Shenhua FC, Shanghai 201315, China.

Medical Services FC Barcelona, 08014 Barcelona, Spain.

出版信息

Nutrients. 2022 Apr 26;14(9):1811. doi: 10.3390/nu14091811.

DOI:10.3390/nu14091811
PMID:35565783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9104583/
Abstract

Evidence exists to suggest that ROS induce muscular injury with a subsequent decrease in physical performance. Supplementation with certain antioxidants is important for physically active individuals to hasten recovery from fatigue and to prevent exercise damage. The use of nutritional supplements associated with exercise, with the aim of improving health, optimizing training or improving sports performance, is a scientific concern that not only drives many research projects but also generates great expectations in the field of their application in pathology. Since its discovery in the 1970s, coenzyme Q (CoQ) has been one of the most controversial molecules. The interest in determining its true value as a bioenergetic supplement in muscle contraction, antioxidant or in the inflammatory process as a muscle protector in relation to exercise has been studied at different population levels of age, level of physical fitness or sporting aptitude, using different methodologies of effort and with the contribution of data corresponding to very diverse variables. Overall, in the papers reviewed, although the data are inconclusive, they suggest that CoQ supplementation may be an interesting molecule in health or disease in individuals without a pathological deficiency and when used for optimising exercise performance. Considering the results observed in the literature, and as a conclusion of this systematic review, we could say that it is an interesting molecule in sports performance. However, clear approaches should be considered when conducting future research.

摘要

有证据表明,活性氧会导致肌肉损伤,进而导致身体机能下降。对于经常运动的人来说,补充某些抗氧化剂对于从疲劳中迅速恢复并预防运动损伤非常重要。使用与运动相关的营养补充剂,旨在改善健康、优化训练或提高运动表现,这是一个科学关注点,不仅推动了许多研究项目,而且在其在病理学中的应用领域也产生了巨大的期望。自 20 世纪 70 年代发现以来,辅酶 Q(CoQ)一直是最具争议的分子之一。人们一直致力于研究它在肌肉收缩、抗氧化剂或作为运动过程中肌肉保护剂的真正价值,以确定其作为生物能量补充剂的作用,研究对象涉及不同年龄、不同体能水平或运动天赋的人群,采用了不同的努力方法,并结合了非常多样化的变量的数据。总的来说,在回顾的论文中,尽管数据尚无定论,但它们表明,在没有病理缺乏的情况下,辅酶 Q 补充剂可能对健康或疾病个体具有一定的作用,并且可能对优化运动表现有一定的作用。考虑到文献中的观察结果,并作为本系统综述的结论,我们可以说,它是运动表现方面的一个有趣的分子。然而,在进行未来研究时,应该考虑明确的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d20b/9104583/52d420bba29a/nutrients-14-01811-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d20b/9104583/52d420bba29a/nutrients-14-01811-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d20b/9104583/52d420bba29a/nutrients-14-01811-g001.jpg

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