Hadjiyannakis K, Ogilvie R D, Alloway C E, Shapiro C
Department of Psychology, Brock University, St. Catharines, Ontario, Canada.
Electroencephalogr Clin Neurophysiol. 1997 Nov;103(5):543-53. doi: 10.1016/s0013-4694(97)00064-3.
The EEG in REM sleep is markedly different from the EEG in non-REM sleep; however, very little research has been conducted analyzing the transition from NREM to REM sleep. The purpose of this study was to describe the changes in EEG power spectra that coincide with significant physiological events throughout the transition from stage 2 to REM sleep. Furthermore, a comparison of the stage 2 to REM transition between narcoleptic patients and normal sleepers was conducted. Five female and five male patients diagnosed with narcolepsy-cataplexy and 10 normal sleepers matched for age and gender participated. Analyses were based on the consecutive appearance of 3 common physiological indicators of REM sleep: First, a decrease in tonic submental EMG activity; second, the appearance of saw tooth waves; and third, the appearance of rapid eye movements. Systematic changes in EEG power density were evident for delta, theta, alpha and sigma frequencies, across the stage 2-REM transition. These changes appeared to be relatively continuous throughout this transition rather than changing dramatically following the onset of any one of the 3 primary physiological indicators of REM sleep. Furthermore, the transition from stage 2 to stage REM appeared to be similar for narcoleptic patients and normal sleepers.
快速眼动睡眠（REM）期的脑电图（EEG）与非快速眼动睡眠期的脑电图明显不同；然而，针对从非快速眼动睡眠向快速眼动睡眠转变过程进行分析的研究却非常少。本研究的目的是描述在从第2阶段睡眠过渡到快速眼动睡眠的整个过程中，与重大生理事件同时出现的脑电图功率谱变化。此外，还对发作性睡病患者和正常睡眠者从第2阶段到快速眼动睡眠的转变进行了比较。五名患有发作性睡病-猝倒症的女性患者和五名男性患者以及十名年龄和性别匹配的正常睡眠者参与了研究。分析基于快速眼动睡眠的三个常见生理指标的连续出现情况：第一，颏下肌紧张性肌电图（EMG）活动减少；第二，锯齿波出现；第三，快速眼动出现。在整个第2阶段到快速眼动睡眠的转变过程中，脑电图功率密度在δ、θ、α和σ频率上出现了系统性变化。这些变化在整个转变过程中似乎相对连续，而不是在快速眼动睡眠的三个主要生理指标中的任何一个出现后急剧变化。此外，发作性睡病患者和正常睡眠者从第2阶段到快速眼动睡眠阶段的转变似乎相似。
