BE-32030 A, B, C, D and E, new antitumor substances produced by Nocardia sp. A32030.
作者信息
Tsukamoto M, Murooka K, Nakajima S, Abe S, Suzuki H, Hirano K, Kondo H, Kojiri K, Suda H
机构信息
Exploratory Research Laboratories, Tsukuba Research Institute, Banyu Pharmaceutical Co., Ltd., Tsukuba, Japan.
出版信息
J Antibiot (Tokyo). 1997 Oct;50(10):815-21. doi: 10.7164/antibiotics.50.815.
PMID:9402985
Abstract
New antitumor substances, designated BE-32030A, B, C, D and E, were isolated from the culture broth of Nocardia sp. A32030. The active principles were extracted from the mycelium by methanol and purified by Sephadex LH-20 and reversed-phase column chromatographies and finally by reversed-phase HPLC. BE-32030A, B, C, D and E inhibited the growth of P388 murine leukemia, DLD-1 human colon cancer, PC-13 human lung cancer and MKN-45 human stomach cancer cell lines.
摘要
Zotero 插件