Nothramicin, a new anthracycline antibiotic from Nocardia sp. MJ896-43F17.
作者信息
Momose I, Kinoshita N, Sawa R, Naganawa H, Iinuma H, Hamada M, Takeuchi T
机构信息
Institute of Microbial Chemistry, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1998 Feb;51(2):130-5. doi: 10.7164/antibiotics.51.130.
PMID:9544933
Abstract
A new antibiotic designated nothramicin was isolated from the culture broth of Nocardia sp. MJ896-43F17 which was closely related to Nocardia brasiliensis. It was isolated by the Diaion HP-20 column chromatography, butyl acetate extraction and purified by HPLC. It inhibited the growth of mycobacteria at the concentration of 1.56 approximately 25 microg/ml. Nothramicin was revealed to be a new member of anthracycline antibiotics by the various spectroscopies.
摘要
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