Herry I, Philippe B, Hennequin C, Danel C, Lejeunne C, Meyer G
Service de Pneumologie, Hôpital Laennec, Paris, France.
Chest. 1997 Dec;112(6):1692-3. doi: 10.1378/chest.112.6.1692.
An unusual case of life-threatening visceral larva migrans (toxocariasis) is reported herein. The patient was admitted with acute dyspnea and bilateral pleural effusion; rapidly pericardial tamponade developed. Blood and body fluid eosinophilia were elevated. Extensive investigations revealed no malignant process or vasculitis, but Toxocara infection was confirmed by rising specific antibody titers. The high seroprevalence of Toxocara antibodies, particularly in children, suggests that a diagnosis of visceral larva migrans should be considered before a diagnosis of systemic hypereosinophilic syndrome even when clinical presentation is unusual. Prophylaxis against this widespread polymorphic zoonotic infection is desirable in view of the potentially dramatic consequences of infestation.
本文报告了一例罕见的危及生命的内脏幼虫移行症（弓蛔虫病）病例。患者因急性呼吸困难和双侧胸腔积液入院；很快出现心包填塞。血液和体液中的嗜酸性粒细胞增多。广泛检查未发现恶性病变或血管炎，但特异性抗体滴度升高证实了弓蛔虫感染。弓蛔虫抗体的高血清阳性率，尤其是在儿童中，表明即使临床表现不寻常，在诊断系统性嗜酸性粒细胞增多综合征之前也应考虑内脏幼虫移行症的诊断。鉴于这种广泛的多形性人畜共患感染可能产生的严重后果，对其进行预防是可取的。
