Schneider U, Gelisken F, Inhoffen W, Kreissig I
Department of Ophthalmology III (Retina and Vitreous Surgery), University Eye Clinic, Tübingen, Germany.
Int Ophthalmol. 1997;21(2):79-85. doi: 10.1023/a:1005848806641.
To determine the role of indocyanine green angiography (ICGA) in the prediction of the development of choroidal neovascularization (CNV).
We reviewed the ICG angiograms of 124 patients with newly diagnosed unilateral occult CNV secondary to age-related macular degeneration (AMD) in whom the fellow eye had only drusen by biomicroscopy and fluorescein angiography. Follow-up data of at least 12 months were obtained in all eyes.
113 fellow eyes had a normal ICG study, while 11 fellow eyes revealed plaque-like late hyperfluorescence. During an average follow-up time of 18.2 months exudative AMD developed in 7 of 11 eyes with late hyperfluorescence on ICGA and in 6 of 113 with a normal ICGA study.
ICGA may help to predict which fellow eyes are at higher risk of developing future exudative changes.
确定吲哚菁绿血管造影（ICGA）在预测脉络膜新生血管（CNV）发生发展中的作用。
我们回顾了124例新诊断为单侧隐匿性CNV继发于年龄相关性黄斑变性（AMD）患者的ICG血管造影片，这些患者的对侧眼通过生物显微镜检查和荧光素血管造影仅发现有玻璃膜疣。所有眼睛均获得了至少12个月的随访数据。
113只对侧眼ICG检查正常，而11只对侧眼显示出斑块状晚期高荧光。在平均18.2个月的随访期内，ICGA显示晚期高荧光的11只眼中有7只发生了渗出性AMD，ICG检查正常的113只眼中有6只发生了渗出性AMD。
ICGA可能有助于预测哪些对侧眼发生未来渗出性改变的风险更高。
