光学相干断层扫描血管造影术用于检测年龄相关性黄斑变性中的非渗出性黄斑新生血管形成
Optical Coherence Tomography Angiography for Detecting Nonexudative Macular Neovascularization in Age-Related Macular Degeneration.
作者信息
Greenberg Jeremy R, Kim Brian Y, Brady Christopher J, Millay Robert H, Raut Robert
机构信息
Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA.
Department of Ophthalmology, University of Vermont Medical Center, Burlington, VT, USA.
出版信息
J Vitreoretin Dis. 2022 Dec 9;7(1):16-19. doi: 10.1177/24741264221126297. eCollection 2023 Jan-Feb.
PURPOSE
To compare the efficacy of optical coherence tomography angiography (OCTA) and indocyanine green angiography (ICGA) for detecting nonexudative macular neovascularization (MNV) in age-related macular degeneration (AMD).
METHODS
In this prospective study, patients with a new diagnosis of exudative AMD in 1 eye were imaged using OCTA, fluorescein angiography (FA), and ICGA in both eyes. The rates at which these imaging modalities detected nonexudative MNV in the nonexudative fellow eye were then compared.
RESULTS
This study comprised 41 eyes with a mean follow-up was 14 months. Nonexudative MNV was found in 3 eyes using OCTA and ICGA. No MNV exudation was detected on FA or structural OCT. One of 3 eyes with MNV progressed to exudative disease 6 months after the initial visit. During the follow-up, 5 of the 38 eyes without MNV developed exudation at 4 to 18 months.
CONCLUSIONS
OCTA is similarly effective as ICGA at detecting nonexudative MNV patterns.
目的
比较光学相干断层扫描血管造影（OCTA）和吲哚菁绿血管造影（ICGA）在检测年龄相关性黄斑变性（AMD）中非渗出性黄斑新生血管（MNV）方面的疗效。
方法
在这项前瞻性研究中，对1只眼新诊断为渗出性AMD的患者双眼进行OCTA、荧光素血管造影（FA）和ICGA检查。然后比较这些成像方式在对侧非渗出性眼中检测非渗出性MNV的比率。
结果
本研究纳入41只眼，平均随访14个月。使用OCTA和ICGA在3只眼中发现了非渗出性MNV。在FA或结构性OCT上未检测到MNV渗出。3只患有MNV的眼中有1只在初次就诊6个月后进展为渗出性疾病。在随访期间，38只无MNV的眼中有5只在4至18个月时出现渗出。
结论
在检测非渗出性MNV模式方面，OCTA与ICGA同样有效。
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