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[Substituted thio-arylidene thiazolidinones: synthesis and structural study].

作者信息

Albuquerque J F, Galdino S L, Chantegrel J, Thomasson F, Pitta I R, Luu-Duc C

机构信息

Departamento de Antibioticos, Universidade Federal de Pernambuco, Cidade Universitaria, Recife, Brasil.

出版信息

Ann Pharm Fr. 1997;55(5):201-5.

PMID:9406468
Abstract

The synthesis and physico-chemical properties of fourteen 4-thio-5-arylidene-thiazolidine-2-ones and eight 3-(4-bromophenacyl)-4-thio-5-arylidene-thiazolidine-2-ones are described. These products were synthetized by the aldolisation-crotonisation reaction between aromatic aldehydes and 4-thio-thiazolidine-2-one followed by N-alkylation of this substituted compounds.

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