Albuquerque J F, Galdino S L, Chantegrel J, Thomasson F, Pitta I R, Luu-Duc C
Departamento de Antibioticos, Universidade Federal de Pernambuco, Cidade Universitaria, Recife, Brasil.
Ann Pharm Fr. 1997;55(5):201-5.
The synthesis and physico-chemical properties of fourteen 4-thio-5-arylidene-thiazolidine-2-ones and eight 3-(4-bromophenacyl)-4-thio-5-arylidene-thiazolidine-2-ones are described. These products were synthetized by the aldolisation-crotonisation reaction between aromatic aldehydes and 4-thio-thiazolidine-2-one followed by N-alkylation of this substituted compounds.