Krieger M D, Chandrasoma P T, Zee C S, Apuzzo M L
Department of Neurosurgery, University of Southern California, Los Angeles, USA.
Semin Surg Oncol. 1998 Jan-Feb;14(1):13-25. doi: 10.1002/(sici)1098-2388(199801/02)14:1<13::aid-ssu3>3.0.co;2-5.
Stereotactic biopsy has evolved as a powerful and safe tool to provide tissue diagnoses with minimal disruption of normal functioning brain. It plays a significant role in the management of malignant brain tumors, where the benefit of open surgery might not justify the concomitant risks. Stereotactic procedures are closed procedures, and thus direct feedback is not provided to the surgeon during manipulation of brain tissue. This difference from most other neurosurgical procedures necessitates rigor in the preoperative workup, the planning of the procedure, and the conduct of the procedure. The success of the procedure is measured by the ability of the team to make an accurate histopathological diagnosis of the lesion; in experienced hands, the rate of success should exceed 95%. Complications and mortality can be minimized with appropriate attention to detail.
立体定向活检已发展成为一种强大且安全的工具，能够在对正常功能的脑组织造成最小干扰的情况下提供组织诊断。它在恶性脑肿瘤的治疗中发挥着重要作用，因为开颅手术的益处可能无法抵消其伴随的风险。立体定向手术是闭合性手术，因此在操作脑组织过程中不会为外科医生提供直接反馈。与大多数其他神经外科手术的这种差异使得在术前检查、手术规划和手术实施过程中都必须严谨。该手术的成功与否通过团队对病变做出准确组织病理学诊断的能力来衡量；在经验丰富的医生手中，成功率应超过95%。通过对细节给予适当关注，并发症和死亡率可以降至最低。
