亚磷酸三苯酯和2,2'-联吡啶二硒醚作为偶联试剂在寡核苷酸合成中的联合应用。
A combined use of triphenyl phosphite and 2,2'-dipyridyl diselenide as a coupling reagent in oligonucleotide synthesis.
作者信息
Takaku H, Shimida Y, Nakajima Y, Hata T
出版信息
Nucleic Acids Res. 1976 May;3(5):1233-48. doi: 10.1093/nar/3.5.1233.
Abstract
Oligonucleotides and nucleoside phosphoramidates can be synthesized in high yields by a combined use of triphenyl phosphite and 2,2'-dipyridyl diselenide as a coupling reagent.
摘要
通过联合使用亚磷酸三苯酯和2,2'-二吡啶二硒醚作为偶联试剂，可以高产率地合成寡核苷酸和核苷亚磷酰胺。
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