代谢性酸中毒对慢性肾衰竭患儿血清载脂蛋白A I和载脂蛋白B水平的影响。

The effect of metabolic acidosis on serum apolipoprotein A I and apolipoprotein B levels in children with chronic renal failure.

作者信息

Bircan Z, Kaplan A, Soran M, Söker M, Kervancioğlu M, Sahin A, Kilinc M

机构信息

Dicle University Hospital Paediatrics, Biochemistry and Statistics, Diyarbakir, Turkey.

出版信息

Int Urol Nephrol. 1997;29(5):603-7. doi: 10.1007/BF02552208.

DOI:10.1007/BF02552208

PMID:9413770

Abstract

In this report serum apolipoprotein A I (Apo A I) and apolipoprotein B (Apo B) levels were determined in children with chronic renal disease (CRD) during metabolic acidosis, after the correction of metabolic acidosis and in healthy children to look for the effect of metabolic acidosis on Apo A I and B levels. It was found that Apo A I levels were significantly decreased during metabolic acidosis (p < 0.05) but Apo A I/Apo B ratios were not affected before and after the correction of acidosis in the CRD group (p > 0.05) although it was significantly different from those in the controls (p < 0.01).

摘要

在本报告中，测定了慢性肾病（CRD）患儿在代谢性酸中毒期间、代谢性酸中毒纠正后以及健康儿童的血清载脂蛋白A I（Apo A I）和载脂蛋白B（Apo B）水平，以探究代谢性酸中毒对Apo A I和B水平的影响。结果发现，CRD组在代谢性酸中毒期间Apo A I水平显著降低（p < 0.05），但酸中毒纠正前后Apo A I/Apo B比值未受影响（p > 0.05），尽管与对照组相比差异显著（p < 0.01）。