Kishimoto S, Takenaka H, Shibagaki R, Nagata M, Yasuno H
Department of Dermatology, Kyoto Prefectural University of Medicine, Japan.
Br J Dermatol. 1997 Nov;137(5):816-20.
We report the clinical, light microscopic, immunohistochemical and ultrastructural features of a verruciform xanthoma that developed in association with a vulval fibroepithelial polyp. To our knowledge, this is the first time that this association has been reported. Immunohistochemical findings confirmed that the xanthoma cells were of a monocyte/macrophage lineage. In addition to typical histological characteristics, prominent vascular ectasias were detected in the deep dermis at the periphery of this lesion. The ectasias may play a part in pathogenesis.
我们报告了一例与外阴纤维上皮性息肉相关的疣状黄瘤的临床、光镜、免疫组化及超微结构特征。据我们所知，这是首次报道这种关联。免疫组化结果证实黄瘤细胞来源于单核细胞/巨噬细胞谱系。除了典型的组织学特征外，在该病变周边的真皮深层检测到明显的血管扩张。这些扩张可能在发病机制中起作用。
