Caucci M, Barbatelli G, Cinti S
G. Salesi Children's Hospital, Ancona, Italy.
Fertil Steril. 1997 Dec;68(6):1051-8. doi: 10.1016/s0015-0282(97)00410-x.
To determine the functional state of the testes of young adults treated for small and hypotrophic retractile testis at prepubertal age by orchiopexy and/or hormonal therapy and the functional state of the testes of adults with retractile testis.
Spermiogram and transmission electron microscopy (TEM) study of the semen. Light microscopic and TEM studies of semen and testicular biopsies of adult with retractile testis were performed.
Division of Pediatric Surgery in an academic environment.
PATIENT(S): Thirty-eight young adults (mean age, 18 years) treated for retractile testis at prepubertal age and seven adults (mean age, 28 years) with retractile testis.
INTERVENTION(S): Two cycles of hCG, followed by surgical therapy (orchiopexy) when unsuccessful.
MAIN OUTCOME MEASURE(S): Fertility of young adults treated for retractile testis at prepubertal age.
RESULT(S): Only 8 of 38 (21%) young adults had normal spermiograms. Five of 38 (13%) were azoospermic and 25 of 38 (66%) were oligoasthenozoospermic with ultrastructural signs of altered maturation of the sperm and a higher number of atypical forms. Of the adults with retractile testis, 2 of 7 (28.5%) were normal, 3 of 7 (43%) were oligoasthenozoospermic, and 2 of 7 (28%) were azoospermic.
CONCLUSION(S): Our data support the hypothesis that prepubertal retractile testis showing signs of reduced consistency and size is a risk factor for adult infertility and requires treatment.
确定青春期前因小而萎缩性回缩睾丸接受睾丸固定术和/或激素治疗的年轻成年人的睾丸功能状态，以及回缩睾丸成年男性的睾丸功能状态。
精液的精子图和透射电子显微镜（TEM）研究。对回缩睾丸成年男性的精液和睾丸活检进行了光学显微镜和TEM研究。
学术环境中的小儿外科。
38名青春期前因回缩睾丸接受治疗的年轻成年人（平均年龄18岁）和7名回缩睾丸成年男性（平均年龄28岁）。
两个周期的人绒毛膜促性腺激素（hCG），若不成功则进行手术治疗（睾丸固定术）。
青春期前因回缩睾丸接受治疗的年轻成年人的生育能力。
38名年轻成年人中只有8名（21%）精子图正常。38名中有5名（13%）无精子症，38名中有25名（66%）为少弱精子症，精子成熟改变有超微结构体征且非典型形态数量较多。在回缩睾丸成年男性中，7名中有2名（28.5%）正常，7名中有3名（43%）为少弱精子症，7名中有2名（28%）无精子症。
我们的数据支持以下假设，即青春期前回缩睾丸出现质地变软和体积变小迹象是成年期不育的危险因素，需要进行治疗。
