Rasmussen P E, Erb K, Westergaard L G, Laursen S B
Department of Obstetrics and Gynaecology, Odense University Hospital, Denmark.
Fertil Steril. 1997 Dec;68(6):1059-64. doi: 10.1016/s0015-0282(97)00377-4.
To compare the quality of semen in 1,055 Danish men born between 1950 and 1970 who are assumed to represent a random sample of the Danish male population of fertile age.
Retrospective review of data on semen quality at the time of the female partner's first IVF treatment.
The Fertility Clinic, Odense University Hospital, Odense, Denmark.
PATIENT(S): One thousand fifty-five male partners of women with tubal infertility who were referred for IVF treatment consecutively during the period 1990-1996.
INTERVENTION(S): Analysis of the semen samples delivered and used in connection with the couples' first IVF treatment.
MAIN OUTCOME MEASURE(S): Year of birth, age at time of sample collection, sperm concentration, and semen volume.
RESULT(S): The mean sperm concentration (+/- SD) was 183.7 x 10(6) mL and the mean semen volume (+/- SD) was 3.9 mL. A considerable variation in both parameters was found from year to year, but no significant change occurred in either parameter throughout the entire period. When four birth cohorts were compared, a later year of birth was not associated with any change in sperm concentration or semen volume.
CONCLUSION(S): Sperm concentration and semen volume were not related to year of birth, indicating that sperm quality has not changed in the Danish male population during the last 20-30 years.
比较1950年至1970年出生的1055名丹麦男性的精液质量，这些男性被认为代表了丹麦育龄男性人口的随机样本。
对女性伴侣首次接受体外受精（IVF）治疗时的精液质量数据进行回顾性分析。
丹麦欧登塞市欧登塞大学医院生育诊所。
1990年至1996年期间连续被转诊接受IVF治疗的1055名输卵管性不孕女性的男性伴侣。
分析与夫妻首次IVF治疗相关所提供和使用的精液样本。
出生年份、样本采集时的年龄、精子浓度和精液量。
平均精子浓度（±标准差）为183.7×10⁶/mL，平均精液量（±标准差）为3.9 mL。每年这两个参数都有相当大的变化，但在整个期间这两个参数均未发生显著变化。当比较四个出生队列时，出生年份较晚与精子浓度或精液量的任何变化均无关联。
精子浓度和精液量与出生年份无关，表明在过去20 - 30年中丹麦男性人口的精子质量没有变化。
