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肾包虫病的组织病理学、临床发现及治疗

Histopathology, clinical findings and treatment of renal hydatidosis.

作者信息

Cirenei A

出版信息

Ann Ital Chir. 1997 May-Jun;68(3):275-84.

PMID:9419907
Abstract

Renal hydatidosis, although not frequent, is the third location of the echinococcus granulosus in the man, after the liver and lungs. Its clinical importance is remarkable as the natural history of the process (if left untreated) usually results in the opening of the parasitic focus into the excretory ducts and the complete destruction of the kidney. In spite of that, insufficient attention is usually dedicated to the topic. So in the lecture the major aspects of the problem have been considered, also on the basis of histological, clinical and radiological personal studies. The site localisation is essential, and at present is possible on combined modality studies, in particular on diagnostic imaging: plain radiography, conventional urography and new imaging procedures, US, CT and MR, give typical images that definitively prove the specific diagnosis. With regard to treatment, the problem at present is still basically surgical: but nephrectomy (as excessively performed in the past) must be if possible avoided and reserved for cases of parenchymal destruction or of untreatable infection). On the contrary, when it is still possible, one must consider conservative techniques, limited to the removal of the parasite and of permanently damaged parenchymal areas. Cystectomy with resection of the exuberant pericystium or (when possible) segmental resection of the kidney offer a good solution, sometimes also in cases of recurrence.

摘要

肾包虫病虽不常见,但在人体中是细粒棘球绦虫感染的第三大部位,仅次于肝和肺。其临床意义显著,因为该疾病的自然病程(若不治疗)通常会导致寄生病灶破溃进入排泄管道,进而使肾脏完全损毁。尽管如此,该话题通常未得到足够重视。因此,在本次讲座中,基于个人的组织学、临床及放射学研究,对该问题的主要方面进行了探讨。病变部位的定位至关重要,目前通过联合检查手段,尤其是诊断性影像学检查可以实现:X线平片、传统尿路造影以及新型成像检查方法,如超声、CT和磁共振成像,均可提供典型图像,从而明确做出特异性诊断。关于治疗,目前该问题基本上仍需外科手术解决:但应尽可能避免过去过度实施的肾切除术,仅在肾实质破坏或存在无法治疗的感染时才考虑采用。相反,在仍可行的情况下,必须考虑采用保守技术,仅限于清除寄生虫及永久性受损的肾实质区域。切除囊肿并切除增生的外囊或(如有可能)进行肾段切除术可提供良好的解决方案,有时对于复发病例也是如此。

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