Kelleher C J, Cardozo L D, Khullar V, Salvatore S
Department of Urogynaecology, King's College Hospital, London, UK.
Br J Obstet Gynaecol. 1997 Dec;104(12):1374-9. doi: 10.1111/j.1471-0528.1997.tb11006.x.
To design and validate a condition-specific quality of life questionnaire for the assessment of women with urinary incontinence, and to use the questionnaire to assess the quality of life of women with specific urodynamic diagnoses.
A tertiary referral urogynaecology unit at King's College Hospital, London.
The questionnaire was designed following six different pilot studies; in this study it was tested for validity and reliability using standard psychometric techniques. The questionnaire was used in 293 consecutive women referred for investigation of urinary incontinence.
The questionnaire was shown to be reliable both by test-retest analysis and by measurement of its internal consistency. The construct of the questionnaire and the answers by respondents confirmed its face and content validity. Criterion validity was measured by correlation with scores obtained on a validated generic measure of quality of life, the Short Form 36. Women with detrusor instability had greater quality of life impairment than women with other urodynamic diagnoses.
The questionnaire was easy for the women to use and was a valid and reliable instrument for the assessment of quality of life in women with urinary incontinence. It will be useful for the rapid appraisal and follow up of women with urinary incontinence in many different clinical settings, including the evaluation of new treatments of urinary incontinence in controlled clinical trials.
设计并验证一份针对尿失禁女性的特定病情生活质量问卷，并使用该问卷评估具有特定尿动力学诊断的女性的生活质量。
伦敦国王学院医院的三级转诊泌尿妇科科室。
该问卷在六项不同的预试验研究后设计而成；在本研究中，使用标准心理测量技术对其有效性和可靠性进行测试。该问卷应用于293名连续转诊来接受尿失禁检查的女性。
通过重测分析和测量其内部一致性，该问卷被证明具有可靠性。问卷的结构和受访者的回答证实了其表面效度和内容效度。通过与已验证的通用生活质量测量工具简短健康调查问卷（Short Form 36）所获分数的相关性来衡量标准效度。逼尿肌不稳定的女性比其他尿动力学诊断的女性生活质量受损更严重。
该问卷对女性来说易于使用，是评估尿失禁女性生活质量的有效且可靠的工具。它将有助于在许多不同临床环境中对尿失禁女性进行快速评估和随访，包括在对照临床试验中评估尿失禁的新治疗方法。
