Verstraete A G, Buylaert W A
Laboratory of Clinical Chemistry, University Hospital, Gent, Belgium.
Eur J Emerg Med. 1995 Dec;2(4):217-23. doi: 10.1097/00063110-199512000-00008.
In a prospective study of 4234 patients with acute poisoning in the Emergency Department of the University Hospital of Gent in Belgium between 1983 and 1990, we observed a decline in the number of poisonings from 665 in 1983 to 424 in 1990. This was due to a decrease in the number of deliberate self-poisonings. Fifty-six per cent of patients were female and the most prevalent age group was 20 to 24 years. There was no seasonal variation. The substances most frequently taken were benzodiazepines (55% of the deliberate self-poisonings), ethanol in combination with other substances (35.8%), barbiturates and older hypnotics (18.6%), non-narcotic analgesics (13.3%) and tricyclic antidepressants (11.6%). Carbon monoxide accounted for 65.1% of all the accidental poisonings. With regard to treatment, a reduction in gastric lavage was observed. The patients were transferred to the intensive care unit (29.2%), the psychiatry ward (23.6%) or discharged home (27.8%). Only 0.3% of the patients died in the Emergency Department.
在1983年至1990年间对比利时根特大学医院急诊科4234例急性中毒患者进行的一项前瞻性研究中，我们观察到中毒病例数从1983年的665例降至1990年的424例。这是由于蓄意自我中毒病例数减少所致。56%的患者为女性，最常见的年龄组为20至24岁。无季节性变化。最常摄入的物质为苯二氮䓬类（占蓄意自我中毒的55%）、乙醇与其他物质联用（35.8%）、巴比妥类及旧的催眠药（18.6%）、非麻醉性镇痛药（13.3%）和三环类抗抑郁药（11.6%）。一氧化碳占所有意外中毒的65.1%。在治疗方面，观察到洗胃次数减少。患者被转入重症监护病房（29.2%）、精神科病房（23.6%）或出院回家（27.8%）。仅0.3%的患者在急诊科死亡。
