• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Cytochrome P-450-mediated oxidation of 2-hydroxyestrogens to reactive intermediates.

作者信息

Nelson S D, Mitchell J R, Dybing E, Sasame H A

出版信息

Biochem Biophys Res Commun. 1976 Jun 21;70(4):1157-65. doi: 10.1016/0006-291x(76)91024-x.

DOI:10.1016/0006-291x(76)91024-x
PMID:942437
Abstract
摘要

相似文献

1
Cytochrome P-450-mediated oxidation of 2-hydroxyestrogens to reactive intermediates.细胞色素P - 450介导的2 - 羟基雌激素氧化为反应性中间体。
Biochem Biophys Res Commun. 1976 Jun 21;70(4):1157-65. doi: 10.1016/0006-291x(76)91024-x.
2
The effect of phenobarbital, 3-methylcholanthrene, and pregnenolone-16 alpha-carbonitrile on the N-demethylation and O-de-ethylation of [6-H3]ethylmorphine.苯巴比妥、3-甲基胆蒽及孕烯醇酮-16α-腈对[6-H³]乙基吗啡N-去甲基化和O-去乙基化的影响。
Drug Metab Dispos. 1981 Sep-Oct;9(5):483-4.
3
Enzyme induction with pregnenolone-16 alpha-carbonitrile--onset of action and effect of thioacetamide.孕烯醇酮-16α-腈的酶诱导作用——硫代乙酰胺的起效时间及效果
Biochem Pharmacol. 1974 Apr 1;23(7):1221-3. doi: 10.1016/0006-2952(74)90298-6.
4
Tetrachloroethylene metabolism by the hepatic microsomal cytochrome P-450 system.四氯乙烯通过肝脏微粒体细胞色素P-450系统进行代谢。
Biochem Pharmacol. 1980 Oct 15;29(20):2863-9. doi: 10.1016/0006-2952(80)90023-4.
5
Regulation and properties of a sex-specific hydroxylase system in female rat liver microsomes active on steroid sulfates. I. General characteristics.雌性大鼠肝微粒体中对甾体硫酸盐有活性的性别特异性羟化酶系统的调节与特性。I. 一般特征。
J Biol Chem. 1974 Mar 25;249(6):1940-5.
6
Pregnenolone-16alpha-carbonitrile-inducible cytochrome P450 in rat liver.孕烯醇酮-16α-腈诱导的大鼠肝脏细胞色素P450
Res Commun Chem Pathol Pharmacol. 1976 Nov;15(3):553-62.
7
Metabolism of 2-hydroxyoestrogen methyl ethers in the rat liver in vitro.大鼠肝脏体外对2-羟基雌激素甲醚的代谢
Hoppe Seylers Z Physiol Chem. 1973 Jul;354(7):771-80. doi: 10.1515/bchm2.1973.354.2.771.
8
Chemical synthesis of six novel 17beta-estradiol and estrone dimers and study of their formation catalyzed by human cytochrome P450 isoforms.
J Med Chem. 2007 Nov 1;50(22):5372-81. doi: 10.1021/jm0707323. Epub 2007 Oct 9.
9
Influence of three inducers on rabbit gamma-glutamyltransferase.三种诱导剂对兔γ-谷氨酰转移酶的影响。
Pharmacol Res Commun. 1980 Jun;12(6):557-65. doi: 10.1016/s0031-6989(80)80141-x.
10
Separation, purification, and characterization of a novel form of hepatic cytochrome P-450 from rats treated with pregnenolone-16 alpha-carbonitrile.从孕烯醇酮-16α-腈处理的大鼠中分离、纯化和鉴定一种新型肝细胞色素P-450
J Biol Chem. 1980 Feb 25;255(4):1279-85.

引用本文的文献

1
Estrogen- and stress-induced DNA damage in breast cancer and chemoprevention with dietary flavonoid.雌激素和应激诱导的乳腺癌DNA损伤以及膳食类黄酮的化学预防作用。
Genes Environ. 2017 Feb 1;39:10. doi: 10.1186/s41021-016-0071-7. eCollection 2017.
2
Formation of two novel estrogen guanine adducts and HPLC/MS detection of 4-hydroxyestradiol-N7-guanine in human urine.两种新型雌激素鸟嘌呤加合物的形成及人尿中4-羟基雌二醇-N7-鸟嘌呤的高效液相色谱/质谱检测
Chem Res Toxicol. 2008 Aug;21(8):1622-30. doi: 10.1021/tx800145w. Epub 2008 Jun 27.
3
2-Hydroxylation of ethinyloestradiol in relation to the oxidation of sparteine and antipyrine.
乙炔雌二醇的2-羟基化与司巴丁和安替比林氧化的关系。
Br J Clin Pharmacol. 1984 Oct;18(4):603-7. doi: 10.1111/j.1365-2125.1984.tb02511.x.
4
Clinical implications of enzyme induction and enzyme inhibition.酶诱导和酶抑制的临床意义。
Clin Pharmacokinet. 1981 Jan-Feb;6(1):1-24. doi: 10.2165/00003088-198106010-00001.
5
The metabolism of 17 alpha-ethinyloestradiol by human liver microsomes: formation of catechol and chemically reactive metabolites.人肝微粒体对17α-乙炔雌二醇的代谢：儿茶酚及化学反应性代谢产物的形成
Br J Clin Pharmacol. 1987 Apr;23(4):447-53. doi: 10.1111/j.1365-2125.1987.tb03074.x.
6
Low serum selenium concentration and glutathione peroxidase activity in intrahepatic cholestasis of pregnancy.妊娠肝内胆汁淤积症患者血清硒浓度及谷胱甘肽过氧化物酶活性降低。
Br Med J (Clin Res Ed). 1987 Jan 17;294(6565):150-2. doi: 10.1136/bmj.294.6565.150.
7
Semiquinone anion radicals of catechol(amine)s, catechol estrogens, and their metal ion complexes.儿茶酚（胺）、儿茶酚雌激素及其金属离子络合物的半醌阴离子自由基。
Environ Health Perspect. 1985 Dec;64:185-98. doi: 10.1289/ehp.8564185.
8
Effects of chlorpromazine and its dihydroxy metabolite on calcium movement and electrical activity in superior cervical ganglia.
Arch Toxicol. 1985 Feb;56(4):272-8. doi: 10.1007/BF00295167.
9
Decreased liver cytochrome P-450 in rats caused by norethindrone or ethynyloestradiol.炔诺酮或炔雌醇导致大鼠肝脏细胞色素P - 450减少。
Biochem J. 1977 Jul 15;166(1):57-64. doi: 10.1042/bj1660057.
10
Drug interactions during metabolism in the liver.肝脏代谢过程中的药物相互作用。
Naunyn Schmiedebergs Arch Pharmacol. 1977;297 Suppl 1:S33-4. doi: 10.1007/BF00587769.