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[内镜下脑室造瘘术治疗梗阻性脑积水]

[Endoscopic ventriculostomy in the treatment of obstructive forms of hydrocephalus].

作者信息

Melikian A G, Golanov A V, Shcherbakova E Ia

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 1997 Jul-Sep(3):22-7.

PMID:9424949
Abstract

Third ventriculostomy creating a pathway for the CSF from the third ventricle to the interpeduncular cistern is a rational and sound alternative to the implantation of the shunting system, including Torkildsen shunts in managing obstructive hydrocephalus. Twenty four patients with hydrocephalus aged from 6 to 46 (mean 21 year) were operated. In 20 patients the occlusion was caused by small tumors in the aqueduct area, in 4 cases the occlusion was due to non-neoplastic process. In the majority of cases (19 patients) third ventriculostomy was the first operation for hydrocephalus. A rigid ventriculoscope (K. Storz, Germany) with an external diameter of 6 mm was used in all procedures. In 23 patients a rapid clinical improvement was observed along with resolution of intracranial hypertension. Median follow-up of 7 months duration was possible in 18 cases. 16 patients remain stable with no signs of hydrocephalus. Control MRI studies showed patent ventriculostomy. 5 patients after an endoscopic procedure were treated with irradiation for tumors. In 2 patients the opening in the ventricular floor fused and became nonfunctional. It happened 4 months after fenestration followed by surgical removal of tumors of the pineal region which caused occlusion. Complications were observed in 2 cases. In one patient ventriculitis developed shortly after the procedure and resolved completely by the end of the second postoperative week. Another patient was noted to have signs of transitory moderate diabetes insipidus.

摘要

第三脑室造瘘术为脑脊液从第三脑室流向脚间池开辟了一条通路,是一种合理且可靠的替代分流系统植入的方法,包括在治疗梗阻性脑积水时使用的托尔基尔德森分流术。对24例年龄在6至46岁(平均21岁)的脑积水患者进行了手术。20例患者的梗阻是由导水管区域的小肿瘤引起的,4例患者的梗阻是由于非肿瘤性病变。在大多数病例(19例患者)中,第三脑室造瘘术是治疗脑积水的首次手术。所有手术均使用外径为6毫米的硬质脑室镜(德国卡尔·史托斯公司生产)。23例患者临床症状迅速改善,颅内高压得到缓解。18例患者进行了为期7个月的中位随访。16例患者病情稳定,无脑积水迹象。对照MRI检查显示脑室造瘘口通畅。5例患者在内镜手术后接受了肿瘤放疗。2例患者脑室底部的开口愈合且失去功能。这发生在开窗术后4个月,随后进行了松果体区肿瘤切除术,该肿瘤导致了梗阻。观察到2例并发症。1例患者在手术后不久发生脑室炎,在术后第二周结束时完全消退。另1例患者出现短暂性中度尿崩症的症状。

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Zh Vopr Neirokhir Im N N Burdenko. 1997 Jul-Sep(3):22-7.
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