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[长期情绪应激在高胆固醇血症和高血压发生中的作用]

[The role of prolonged emotional stress in the genesis of hypercholesterolemia and hypertension].

作者信息

Iastrebtsova N L, Simutenko L V

出版信息

Biull Eksp Biol Med. 1976 Jan;81(1):20-1.

PMID:942865
Abstract

Stable endogenous hypercholesterolemia and a slight, but stable hypertension developed under conditions of unrestricted behaviour in rabbits subjected for 4 months to daily prolonged (2-hour) interrupted stimulation of negative emotional zones of the hypothalamus through the implanted electrodes. Changes in cholesterol content were more noticable in case the stimulation was continued against the background of daily feeding of these rabbits with small doses of methylthiouracil.

摘要

在4个月的时间里,通过植入电极每天对家兔下丘脑的负性情绪区进行长时间(2小时)的间断刺激,在家兔行为不受限制的情况下,出现了稳定的内源性高胆固醇血症和轻微但稳定的高血压。如果在给这些家兔每日喂食小剂量甲硫氧嘧啶的背景下继续进行刺激,胆固醇含量的变化会更明显。

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