Vickers A J, Fisher P, Smith C, Wyllie S E, Lewith G T
Division of Public Health and Primary Care, University of Oxford, Radcliffe Infirmary, United Kingdom.
Br J Sports Med. 1997 Dec;31(4):304-7. doi: 10.1136/bjsm.31.4.304.
To pilot a model for determining whether a homoeopathic medicine is superior to placebo for delayed onset muscle soreness (DOMS).
Randomised double blind placebo controlled trial.
Physiotherapy department of a homoeopathic hospital.
Sixty eight healthy volunteers (average age 30; 41% men) undertook a 10 minute period of bench stepping carrying a small weight and were randomised to a homoeopathic medicine or placebo.
Mean muscle soreness in the five day period after the exercise test, symptom free days, maximum soreness score, days to no soreness, days on medication.
The difference between group means was 0.17 in favour of placebo with 95% confidence intervals +/- 0.50. Similar results were found for other outcome measures.
The study did not find benefit of the homoeopathic remedy in DOMS. Bench stepping may not be an appropriate model to evaluate the effects of a treatment on DOMS because of wide variation between subject soreness scores.
试行一种用于确定顺势疗法药物治疗延迟性肌肉酸痛（DOMS）是否优于安慰剂的模型。
随机双盲安慰剂对照试验。
一家顺势疗法医院的理疗科。
68名健康志愿者（平均年龄30岁；41%为男性）进行了10分钟携带小重量的台阶试验，并被随机分配接受顺势疗法药物或安慰剂。
运动试验后五天内的平均肌肉酸痛程度、无症状天数、最大酸痛评分、疼痛消失天数、用药天数。
组间均值差异为0.17，有利于安慰剂，95%置信区间为±0.50。其他观察指标也得到了类似结果。
该研究未发现顺势疗法药物对DOMS有疗效。由于受试者酸痛评分差异较大，台阶试验可能不是评估治疗对DOMS效果的合适模型。
