Bruckdorfer K R
Department of Biochemistry and Molecular Biology, Royal Free Hospital School of Medicine, University of London, UK.
Prostaglandins Leukot Essent Fatty Acids. 1997 Oct;57(4-5):493-7. doi: 10.1016/s0952-3278(97)90434-8.
Oxidation of plasma lipoproteins may play an important role in atherogenesis, but there are also indications that that this process of oxidation may influence other facets of cardiovascular disease, namely blood flow and thrombosis. The evidence that oxidation of low-density lipoproteins may modulate the action of the native lipoproteins with respect to endothelium-dependent relaxation, platelet activation and tissue factor activity is reviewed.
血浆脂蛋白的氧化可能在动脉粥样硬化形成过程中起重要作用，但也有迹象表明这种氧化过程可能会影响心血管疾病的其他方面，即血流和血栓形成。本文综述了低密度脂蛋白氧化可能调节天然脂蛋白在内皮依赖性舒张、血小板活化和组织因子活性方面作用的证据。
