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儿童良性血管肿瘤和血管畸形:1127例回顾性分析

Benign vascular tumors and vascular malformations in childhood: a retrospective analysis of 1127 cases.

作者信息

Akyüz C, Yariş N, Kutluk M T, Büyükpamukçu M

机构信息

Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Turk J Pediatr. 1997 Oct-Dec;39(4):435-45.

PMID:9433144
Abstract

Vascular lesions in childhood are classified as vascular malformations and hemangiomas. Vascular malformations are congenital abnormalities thought to arise from defects during embryological development of vascular tissue. Hemangiomas are benign tumors of vascular endothelium and can spontaneously become involuted in almost all cases. One thousand one hundred and twenty-seven patients with vascular lesions were followed by the Department of Pediatric Oncology, Hacettepe University, for 19 years. Diagnosis was based mainly on history, clinical condition and follow-up data in 98.2 percent of cases. The distribution of the vascular lesions was as follows: 969 patients had hemangiomas, 120 had lymphatic malformations, 18 had combined vascular malformations, 11 had venous malformations, six had port-wine stain, and three had angiokeratoma. Except for ten cases with Klippel-Trenaunay Weber syndrome, vascular malformations were not accompanied by any syndrome.

摘要

儿童期血管病变分为血管畸形和血管瘤。血管畸形是先天性异常,被认为是由于血管组织胚胎发育过程中的缺陷引起的。血管瘤是血管内皮的良性肿瘤,几乎在所有病例中都可自发消退。哈杰泰佩大学儿科肿瘤学系对1127例血管病变患者进行了19年的随访。98.2%的病例诊断主要基于病史、临床状况和随访数据。血管病变的分布如下:969例患有血管瘤,120例患有淋巴管畸形,18例患有复合型血管畸形,11例患有静脉畸形,6例患有葡萄酒色斑,3例患有血管角化瘤。除10例患有克-特-韦综合征外,血管畸形不伴有任何综合征。

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