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[卡比多巴对周围组织肾上腺素能神经纤维中去甲肾上腺素水平的影响]

[Influence of carbidine on the noradrenaline level in the adrenergic nerve fibers in the peripheral tissues].

作者信息

Arefolov V A, Panasiuk L V

出版信息

Farmakol Toksikol. 1976 Jan-Feb;39(1):25-31.

PMID:943316
Abstract

By employing fluorescent histochemistry and spectrofluorimetry the influence of an original psychotropic substance -- carbidine on the level, localization and accumulation of the adrenergic mediator in Vas deferens, dura mater and the kidney capsule was studied "in vivo" and "in vitro". Carbidine was shown to capable of liberating the adrenergic mediator from the sympathetic nerve fibres of the peripheral tissues without affecting the capture and accumulation of exogenous norepinephrine by adrenergic nerve fibres.

摘要

通过荧光组织化学和荧光分光光度法,研究了一种新型精神药物——卡比定对输精管、硬脑膜和肾被膜中肾上腺素能介质的水平、定位和蓄积的“体内”及“体外”影响。结果表明,卡比定能够从外周组织的交感神经纤维中释放肾上腺素能介质,而不影响肾上腺素能神经纤维对外源性去甲肾上腺素的摄取和蓄积。

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