McGrath J W, Hammerschmidt F, Quinn J P
School of Biology and Biochemistry, Queen's University of Belfast, Northern Ireland.
Appl Environ Microbiol. 1998 Jan;64(1):356-8. doi: 10.1128/AEM.64.1.356-358.1998.
The biodegradation by Rhizobium huakuii PMY1 of up to 10 mM phosphonomycin as a carbon, energy, and phosphorus source with accompanying P(i) release is described. This biodegradation represents a further mechanism of resistance to this antibiotic and a novel, phosphate-deregulated route for organophosphonate metabolism by Rhizobium spp.
描述了华癸根瘤菌PMY1对高达10 mM磷霉素的生物降解,磷霉素作为碳源、能源和磷源,同时伴有无机磷(P(i))释放。这种生物降解代表了对该抗生素抗性的另一种机制,也是根瘤菌属对有机膦酸盐代谢的一种新的、不受磷酸盐调控的途径。