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[巴西莱姆病螺旋体病概述]

[Outline of Lyme borreliosis in Brazil].

作者信息

Yoshinari N H, de Barros P J, Bonoldi V L, Ishikawa M, Battesti D M, Pirana S, da Fonseca A H, Schumaker T T

机构信息

Disciplina de Reumatologia, Faculdade de Medicina, Universidade de São Paulo.

出版信息

Rev Hosp Clin Fac Med Sao Paulo. 1997 Mar-Apr;52(2):111-7.

PMID:9435406
Abstract

Since 1989, we have identified 25 patients with Lyme disease, 15 in early and 10 in latent stage, supporting its existence in Brazil, according to following reasons: 1) presence of clinical manifestations compatible with Lyme disease, with cutaneous, articular, nervous system and rarely cardiac envolvement; 2) presence of antibodies against Borrelia burgdorferi; 3) follow up of acute cases show sorologycal changes; 4) good antibiotic response at early stage of disease and only satisfactory in latent form; 5) mapping of risk areas, according to geographycal distribution of patients; 6) presence and identification of Ixodid ticks; 7) identification of micro-organism like borrelias in human, wild animals and ticks cultures, seen by dark field microscope; 8) sorology done in dogs and oxes, confirm existence of risk areas for Lyme disease.

摘要

自1989年以来,我们已确诊25例莱姆病患者,其中15例处于早期,10例处于潜伏期,基于以下原因,这证明了莱姆病在巴西的存在:1)存在与莱姆病相符的临床表现,涉及皮肤、关节、神经系统,心脏受累情况少见;2)存在抗伯氏疏螺旋体的抗体;3)对急性病例的随访显示血清学变化;4)疾病早期对抗生素反应良好,而对潜伏期病例仅反应尚可;5)根据患者的地理分布绘制风险区域图;6)发现并鉴定出硬蜱;7)通过暗视野显微镜在人类、野生动物和蜱虫培养物中鉴定出疏螺旋体等微生物;8)对狗和牛进行的血清学检测证实了存在莱姆病风险区域。

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