Basile Roberta Carvalho, Yoshinari Natalino Hajime, Mantovani Elenice, Bonoldi Virgínia Nazário, Macoris Delphim da Graça, Queiroz-Neto Antonio de
Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal, São Paulo, SP, Brazil.
Universidade de São Paulo, Departamento de reumatologia, São Paulo, SP, Brazil.
Braz J Microbiol. 2017 Jan-Mar;48(1):167-172. doi: 10.1016/j.bjm.2016.09.005. Epub 2016 Oct 4.
Borreliosis caused by Borrelia burgdorferi sensu lato is a cosmopolitan zoonosis studied worldwide; it is called Lyme disease in many countries of the Northern Hemisphere and Lyme-like or Baggio-Yoshinari Syndrome in Brazil. However, despite the increasing number of suspect cases, this disease is still neglected in Brazil by the medical and veterinary communities. Brazilian Lyme-like borreliosis likely involves capybaras as reservoirs and Amblyomma and Rhipicephalus ticks as vectors. Thus, domestic animals can serve as key carriers in pathogen dissemination. This zoonosis has been little studied in horses in Brazil. The first survey was performed in the state of Rio de Janeiro, and this Brazilian Borreliosis exhibits many differences from the disease widely described in the Northern Hemisphere. The etiological agent shows different morphological and genetic characteristics, the disease has a higher recurrence rate after treatment with antibiotics, and the pathogen stimulates intense symptoms such as a broader immune response in humans. Additionally, the Brazilian zoonosis is not transmitted by the Ixodes ricinus complex. With respect to clinical manifestations, Baggio-Yoshinari Syndrome has been reported to cause neurological, cardiac, ophthalmic, muscle, and joint alterations in humans. These symptoms can possibly occur in horses. Here, we present a current panel of studies involving the disease in humans and equines, particularly in Brazil.
由伯氏疏螺旋体狭义种引起的莱姆病是一种在全球范围内研究的世界性人畜共患病；在北半球的许多国家它被称为莱姆病，在巴西则被称为类莱姆病或巴乔 - 吉纳里综合征。然而，尽管疑似病例数量不断增加，但在巴西，该疾病仍被医学和兽医界忽视。巴西类莱姆病疏螺旋体病可能以水豚作为储存宿主，以钝缘蜱属和璃眼蜱属蜱虫作为传播媒介。因此，家畜可作为病原体传播的关键载体。这种人畜共患病在巴西马匹中的研究很少。首次调查在里约热内卢州进行，这种巴西莱姆病与在北半球广泛描述的疾病有许多不同之处。病原体表现出不同的形态和遗传特征，疾病在用抗生素治疗后复发率更高，并且病原体在人类中引发强烈症状，如更广泛的免疫反应。此外，巴西的人畜共患病不是由蓖麻硬蜱复合体传播的。关于临床表现，据报道巴乔 - 吉纳里综合征会导致人类出现神经、心脏、眼科、肌肉和关节改变。这些症状可能在马匹中出现。在此，我们展示了一组目前关于该疾病在人类和马类，特别是在巴西的研究。
