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使用磁共振标记技术评估右心室局部功能:正常人与慢性肺动脉高压患者的比较

Right ventricular regional function using MR tagging: normals versus chronic pulmonary hypertension.

作者信息

Fayad Z A, Ferrari V A, Kraitchman D L, Young A A, Palevsky H I, Bloomgarden D C, Axel L

机构信息

Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, USA.

出版信息

Magn Reson Med. 1998 Jan;39(1):116-23. doi: 10.1002/mrm.1910390118.

DOI:10.1002/mrm.1910390118
PMID:9438445
Abstract

Right ventricular (RV) regional function, in both normal and diseased states, is not well characterized. Using 1D MR myocardial tagging, RV and septal intramyocardial segmental shortening was noninvasively measured in ten healthy subjects and in seven patients with chronic pulmonary hypertension. The normal RV free wall regional shortening was not uniform. A pattern of increasing RV free wall short-axis shortening was found from the RV outflow tract to the RV apex, and a more complex pattern of RV free wall long-axis shortening was observed. Both regional short- and long-axis shortening were globally reduced in pulmonary hypertension patients, with the greatest decreases in the RV outflow tract and in the basal septal wall region. Regional RV function can be quantitatively evaluated using MR tagging to determine the impact of chronic pulmonary hypertension on RV performance.

摘要

无论是在正常状态还是疾病状态下,右心室(RV)的局部功能都尚未得到充分表征。使用一维磁共振心肌标记技术,对10名健康受试者和7名慢性肺动脉高压患者进行了右心室和室间隔心肌内节段缩短的无创测量。正常右心室游离壁局部缩短并不均匀。发现从右心室流出道到右心室心尖,右心室游离壁短轴缩短呈增加趋势,并且观察到右心室游离壁长轴缩短的模式更为复杂。肺动脉高压患者的局部短轴和长轴缩短均整体降低,其中右心室流出道和基底室间隔壁区域降低最为明显。使用磁共振标记技术可以定量评估右心室局部功能,以确定慢性肺动脉高压对右心室功能的影响。

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