Na S K, Park K J, Kim H J, Lee S C
Department of Internal Medicine and Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Korean J Intern Med. 1997 Jun;12(2):242-4. doi: 10.3904/kjim.1997.12.2.242.
Candidiasis has emerged as the most common opportunistic fungal disease over recent decades owing to the progressively increasing use of antibiotics, immunosuppressive and cytotoxic drugs, indwelling foreign bodies and organ transplantation. Hematogenous candida endophthalmitis, which has a characteristic finding of single or multiple fluffy white cotton ball-like chorioretinal lesions often extending into vitreous, is the most fulminant manifestation of systemic candidiasis and may result in blindness. These ocular lesions can be easily recognized on funduscopic examination and should be serially looked for in all patients with known and suspected systemic candidiasis. We report hematogenous candida endophthalmitis in a patient of systemic candidiasis and, to our knowledge, it is the first reported case in our country.
近几十年来,由于抗生素、免疫抑制剂和细胞毒性药物的使用日益增加、体内留置异物以及器官移植,念珠菌病已成为最常见的机会性真菌疾病。血源性念珠菌性眼内炎是系统性念珠菌病最严重的表现形式,其特征性表现为单个或多个蓬松的白色棉球样脉络膜视网膜病变,常延伸至玻璃体,可导致失明。这些眼部病变在眼底检查时很容易识别,所有已知或疑似系统性念珠菌病的患者都应定期进行检查。我们报告了一例系统性念珠菌病患者发生血源性念珠菌性眼内炎,据我们所知,这是我国首例报告病例。