Glazebrook J, Rogers E E, Ausubel F M
Center for Agricultural Biotechnology, University of Maryland, College Park 20742, USA.
Annu Rev Genet. 1997;31:547-69. doi: 10.1146/annurev.genet.31.1.547.
Arabidopsis thaliana (Arabidopsis) is proving to be an ideal model system for studies of host defense responses to pathogen attack. The Arabidopsis genetic system is significantly more tractable than those of other plant species, and Arabidopsis exhibits all of the major kinds of defense responses described in other plants. A large number of virulent and avirulent bacterial, fungal, and viral pathogens of Arabidopsis have been collected. In the last few years, a large number of mutations have been identified in Arabidopsis that cause a wide variety of specific defense-related phenotypes. Analysis of these mutant phenotypes is beginning to give glimpses into the complex signal transduction pathways leading to the induction of the defense responses involved in protecting plants from pathogen infection.
拟南芥正被证明是研究宿主对病原体攻击的防御反应的理想模式系统。拟南芥的遗传系统比其他植物物种的遗传系统更易于处理，并且拟南芥表现出其他植物中描述的所有主要防御反应类型。已经收集了大量拟南芥的毒性和无毒细菌、真菌和病毒病原体。在过去几年中，在拟南芥中鉴定出大量导致各种特定防御相关表型的突变。对这些突变体表型的分析开始让人们初步了解导致诱导参与保护植物免受病原体感染的防御反应的复杂信号转导途径。
