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[用于中内耳听力损失的有源电子听力植入物——耳外科的新时代。III:内耳听力损失的前景]

[Active electronic hearing implants for middle and inner ear hearing loss--a new era in ear surgery. III: prospects for inner ear hearing loss].

作者信息

Zenner H P, Leysieffer H

机构信息

Universitätsklinik für Hals-Nasen-Ohren-Heilkunde, Tübingen.

出版信息

HNO. 1997 Oct;45(10):769-74. doi: 10.1007/s001060050155.

Abstract

The perspectives for active hearing implants lie in the treatment of patients with sensorineural hearing loss (SNHL). The majority of patients with SNHL suffer from a cochlea amplifier (CA) failure which is discernible by a positive recruitment and loss of otoacoustic emissions (OAE). Therefore, the electronic implant is expected to partially replace functions of the CA. Thus, the implant is thought to function as a CAI (cochlea amplifier implant). An approved implant for routine use is not yet available. Clinical studies have thus far only used the high energy consuming (HEC), narrow-band, electromagnetic floating-mass transducer, as well as the Maniglia-HEC implant. The high energie consuming, yet broadband Canadian Fredrickson implant is soon to be used in humans. Of the piezoelectrical implants, a German CAI (Tübingen implant) at present consisting of a piezoelectrical transducer and a microphone has thus far been acutely implanted in first patient. It is a low energy consuming (LEC), broad-band implantable system for patients with sensorineural hearing loss. Routine surgical treatment of patients with sensorineural hearing loss with a CAI will only be achieved if complete implants (with transducer, microphones, batteries, and control unit) are made available. They combine distinct acoustic superiority with invisibility (end of stigmatization), an open ear canal, and hopefully, the end of feedback whistling. Among the implants mentioned, the German CAI is the only LEC implant. Its energy requirements are so low that with today's technologie implantable batteries (e.g., in pacemakers), the additional implantation of an energy carrier seems feasible. Since the implantable microphone is already available in the German system, the only essential part missing for a totally implantable CAI is the implantable control unit.

摘要

有源听力植入设备的前景在于治疗感音神经性听力损失(SNHL)患者。大多数SNHL患者患有耳蜗放大器(CA)故障,这可通过正重振和耳声发射(OAE)丧失来辨别。因此,预计电子植入设备将部分替代CA的功能。这样,该植入设备被认为可作为耳蜗放大器植入物(CAI)发挥作用。目前尚无已获批用于常规使用的植入设备。迄今为止,临床研究仅使用了高能耗(HEC)、窄带、电磁悬浮质量换能器以及马尼利亚-HEC植入物。高能耗但宽带的加拿大弗雷德里克森植入物很快将用于人体试验。在压电植入物中,一种目前由压电换能器和麦克风组成的德国CAI(图宾根植入物)已急性植入首例患者体内。它是一种用于感音神经性听力损失患者的低能耗(LEC)、宽带可植入系统。只有当完整的植入设备(包括换能器、麦克风、电池和控制单元)可用时,才能对感音神经性听力损失患者进行常规的CAI手术治疗。它们兼具明显的声学优势以及隐形效果(消除污名化)、开放耳道,有望还能消除反馈啸叫。在上述提及的植入设备中,德国CAI是唯一的低能耗植入设备。其能量需求极低,以至于采用当今的技术(如用于起搏器的)可植入电池,额外植入一个能量载体似乎是可行的。由于德国系统中已具备可植入麦克风,对于完全可植入的CAI而言,唯一缺失的关键部件就是可植入控制单元。

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