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[采用手术食管去血管化及横断术治疗食管静脉曲张的治疗结果前瞻性评估]

[Prospective evaluation of treatment results while using surgical esophageal devascularization and transection for esophageal varices].

作者信息

Gacyk W, Zadrozny D, Draczkowski T, Kostro J

机构信息

I Katedry i Kliniki Chirurgii Akademii Medycznej w Gdańsku.

出版信息

Wiad Lek. 1997;50 Suppl 1 Pt 1:308-12.

PMID:9446374
Abstract

During the years 1979-1996 over 300 patients aged 2-71, with esophageal varices had been treated in our Clinic. In 104 cases extended gastroesophageal devascularization and esophageal transection combined with splenectomy was performed. According to Child-Pugh's classification 60 patients (58%) were qualified to group A and B, 44 (42%)-to group C. In 61 cases (59%) the operations were carried out electively, in 30 (29%)-as an emergency and in the remaining 13 (12%)-prophylacticly. In all cases the operation was successful in controlling preoperative variceal bleeding. Postoperative mortality amounted in 20 cases (19%): in Child's group A and B-10% and in group C-32%. The highest mortality rate was noted in group C patients operated emergently (38%). The main cause of death was developing hepatic failure (18 cases) and esophageal fistula in the remaining 2. Recurrence of esophageal varices was observed in 4 patients (4%) and the recurrence of variceal bleeding in 3 of them (3%). In other 3 cases recurrent bleeding was caused by acute mucosal lesions in the stomach. No cases of postoperative encephalopathy have been observed. Follow-up period ranged from 2 months to 15 years (mean 6.5 years) and actuarial survival-67 patients (64%). In our opinion esophageal transection with extended gastroesophageal devascularization is an effective method of controlling variceal hemorrhage, with very low recurrence rate and allows to avoid postoperative encephalopathy.

摘要

1979年至1996年间,我院共收治300余例年龄在2至71岁的食管静脉曲张患者。其中104例行扩大的胃食管去血管化联合食管横断术及脾切除术。根据Child-Pugh分级,60例(58%)患者属于A组和B组,44例(42%)属于C组。61例(59%)手术为择期进行,30例(29%)为急诊手术,其余13例(12%)为预防性手术。所有病例手术均成功控制了术前曲张静脉出血。术后死亡率为20例(19%):Child A组和B组为10%,C组为32%。C组急诊手术患者死亡率最高(38%)。主要死亡原因是肝衰竭(18例),其余2例为食管瘘。4例(4%)观察到食管静脉曲张复发,其中3例(3%)出现曲张静脉出血复发。另外3例复发出血是由胃急性黏膜病变引起。未观察到术后脑病病例。随访时间为2个月至15年(平均6.5年),实际存活67例(64%)。我们认为,食管横断联合扩大的胃食管去血管化是控制曲张静脉出血的有效方法,复发率极低,且可避免术后脑病。

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