多巴胺对乙醇戒断的抑制作用。
Suppression of ethanol withdrawal by dopamine.
作者信息
Blum K, Eubanks J D, Wallace J E, Schwertner H A
出版信息
Experientia. 1976 Apr 15;32(4):493-5. doi: 10.1007/BF01920816.
PMID:944645
Abstract
An ethanol-inhalation technique was used to determine a potential relationship between dopamine and central nervous effects produced by alcohol. Both L-DOPA and intracranially injected dopamine resulted in attenuation of ethanol-induced withdrawal convulsion scores, whereas, haloperidol, a known dopaminergic blocker was found to significantly increase convulsion scores.
摘要
采用乙醇吸入技术来确定多巴胺与酒精产生的中枢神经效应之间的潜在关系。左旋多巴和颅内注射多巴胺均能减轻乙醇诱导的戒断惊厥评分，而氟哌啶醇，一种已知的多巴胺能阻滞剂，则被发现会显著提高惊厥评分。
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