来自胃八叠球菌的具有异常连接的寡糖β-葡聚糖。

Oligosaccharide beta-glucans with unusual linkages from Sarcina ventriculi.

作者信息

Lee J, Hollingsworth R I

机构信息

Department of Chemistry, Michigan State University, East Lansing 48824, USA.

出版信息

Carbohydr Res. 1997 Nov 10;304(2):133-41. doi: 10.1016/s0008-6215(97)00204-8.

DOI:10.1016/s0008-6215(97)00204-8

PMID:9449765

Abstract

The structure of a family of unusual glucans from Sarcina ventriculi has been characterized by NMR spectroscopy, methylation analysis, and mass spectrometry. One is a trisaccharide containing a beta-(1-->3) and a beta-(1-->4)-linkage. The other is a hexasaccharide that is simply a 1,4-linkage dimer of the trisaccharide unit. This is the first report of beta-glucan biosynthesis in a Gram-positive organism. Their occurrence in these organisms supports an even more general link between their synthesis and the adaptability of bacteria.

摘要

通过核磁共振光谱、甲基化分析和质谱对来自胃八叠球菌的一族特殊葡聚糖的结构进行了表征。一种是含有β-(1→3)和β-(1→4)连接的三糖。另一种是六糖，它只是三糖单元的1,4-连接二聚体。这是革兰氏阳性生物中β-葡聚糖生物合成的首次报道。它们在这些生物中的出现支持了它们的合成与细菌适应性之间更普遍的联系。